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[免疫酶分析法诊断脑膜炎球菌感染的特异性增强]

[Increased specificity of immunoenzyme analysis for diagnosing meningococcal infection].

作者信息

Zhuravleva G V, Demina A A

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1985 Apr(4):63-6.

PMID:2409722
Abstract

The ELISA test system for the detection of polysaccharide antigens of meningococci, groups A and C, on the basis of the neutralization of specific antibodies has been developed. The specificity of this reaction is determined by the chemically pure preparations of group A and C meningococcal polysaccharides. The sensitivity of this test system based on the neutralization of antibodies is not inferior to that of ELISA with the use of double antiserum.

摘要

基于特异性抗体中和作用的用于检测A群和C群脑膜炎球菌多糖抗原的ELISA检测系统已研发成功。该反应的特异性由A群和C群脑膜炎球菌多糖的化学纯制剂确定。基于抗体中和作用的该检测系统的灵敏度不低于使用双抗血清的ELISA的灵敏度。

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