Geha A S, Krone R J, McCormick J R, Baue A E
J Thorac Cardiovasc Surg. 1975 Sep;70(3):414-31.
Results of direct coronary revascularization with 511 grafts in 213 patients from 1971 to 1974 are reviewed. To improve an early saphenous vein graft (SVG) patency of 84 per cent in the first 85 patients, we have used internal mammary artery grafts (IMAG), when possible, since January, 1973. In 1973 to 1974, 15 patients had SVG's only (36 grafts) and 113 received one or two IMAG's with or without additional SVG's (total 282 grafts); in 26 we used a crossed double IMAG. Forty-seven of 48 patients with unstable angina survived and did well. Flows in SVG's and IMAG's were comparable. Flows in right IMAG's to diagonal or marginal vessels were higher than in right IMAG's to right or left anterior descending (LAD) vessels. In 12 patients with both SVG and IMAG, there was no difference in flow response of either graft to vasoactive drugs. Survival, functional, and patency results with IMAG's were as good as or better than results with SVG's. We conclude that IMAG's yield higher patency and comparable flow rates to SVG's and should be used when the IMA approximates the recipient artery in size and when a high pulsatile free flow is measured from the end of the graft. IMAG's are also safe and feasible for unstable angina.
回顾了1971年至1974年间213例患者使用511支移植物进行直接冠状动脉血运重建的结果。为提高最初85例患者中84%的早期大隐静脉移植物(SVG)通畅率,自1973年1月起,我们尽可能使用了乳内动脉移植物(IMAG)。1973年至1974年,15例患者仅接受了SVG(36支移植物),113例患者接受了一支或两支IMAG,伴或不伴有额外的SVG(共282支移植物);26例患者使用了交叉双IMAG。48例不稳定型心绞痛患者中有47例存活且情况良好。SVG和IMAG的血流相当。右侧IMAG至对角支或钝缘支血管的血流高于右侧IMAG至右或左前降支(LAD)血管的血流。在12例同时使用SVG和IMAG的患者中,两种移植物对血管活性药物的血流反应无差异。IMAG的生存、功能和通畅结果与SVG的结果一样好或更好。我们得出结论,IMAG的通畅率高于SVG,血流速率相当,当乳内动脉(IMA)与受体动脉大小相近且从移植物末端测得高搏动性自由血流时,应使用IMAG。IMAG对于不稳定型心绞痛也是安全可行的。