Hamby R I, Aintablian A, Wisoff B G, Hartstein M L
Am Heart J. 1977 Mar;93(3):306-15. doi: 10.1016/s0002-8703(77)80249-4.
Postoperative coronary bypass flow was evaluated in two groups of randomly selected patients with grafts to the left anterior descending artery (LAD). Saphenous vein bypass grafts were placed in 27 patients and internal mammary artery grafts in 25 patients. Postoperative flow studies were performed in both groups with roentgendensitometric methods based on the transit time of radiopaque media along the graft plus the mean graft diameter. There was no significant difference between the two groups of patients for age, duration of symptoms, or the frequency of hypertension, diabetes mellitus, prior myocardial infarction, or cardiomegaly. Intraoperative bypass flows were 75+/-27 and 77+/-24 ml. per minute for the saphenous vein group (SVG) and internal mammary artery group (IMAG), respectively. There was no significant difference in the heart rate or mean aortic pressure at the time of the roentgendensitometric flow study. The mean graft diameters were 3.0+/-0.5 and 1.9+/-0.3 mm. for the SVG and IMAG, respectively (p less than 0.001). The ratios of graft diameter to LAD diameter were 1.9+/-0.3 and 1.2+/-0.2 for the SVG and IMAG, respectively (p less than 0.001). The roentgendensitometric postoperative flows were 68+/-27 ml. per minute in the SVG and 46+/-16 ml. per minute in the IMAG (p less than 0.01). The present study indicates that flow in significantly higher in saphenous vein than in internal mammary artery bypasses and that the difference in flow may in part be explained on the basis of the graft diameter.
在两组随机选择的接受左前降支(LAD)移植的患者中评估了术后冠状动脉搭桥血流情况。27例患者接受了大隐静脉搭桥移植,25例患者接受了乳内动脉移植。两组均采用基于不透射线介质沿移植物的传输时间加上移植物平均直径的X线密度测定法进行术后血流研究。两组患者在年龄、症状持续时间、高血压、糖尿病、既往心肌梗死或心脏扩大的发生率方面无显著差异。大隐静脉组(SVG)和乳内动脉组(IMAG)术中搭桥血流分别为每分钟75±27毫升和77±24毫升。在进行X线密度测定血流研究时,心率或平均主动脉压无显著差异。SVG和IMAG的移植物平均直径分别为3.0±0.5毫米和1.9±0.3毫米(p<0.001)。SVG和IMAG的移植物直径与LAD直径之比分别为1.9±0.3和1.2±0.2(p<0.001)。SVG术后X线密度测定血流为每分钟68±27毫升,IMAG为每分钟46±16毫升(p<0.01)。本研究表明,大隐静脉搭桥的血流明显高于乳内动脉搭桥,血流差异部分可基于移植物直径来解释。