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鸟分枝杆菌-胞内分枝杆菌、瘰疬分枝杆菌及相关分枝杆菌属菌种α抗原的特异性与分布

Specificity and distribution of alpha antigens of Mycobacterium avium-intracellulare, Mycobacterium scrofulaceum, and related species of mycobacteria.

作者信息

Tasaka H, Nomura T, Matsuo Y

出版信息

Am Rev Respir Dis. 1985 Jul;132(1):173-4. doi: 10.1164/arrd.1985.132.1.173.

DOI:10.1164/arrd.1985.132.1.173
PMID:2409853
Abstract

Specificity of antigenic determinants in alpha antigens of Mycobacterium avium, M. intracellulare, M. scrofulaceum, M. gordonae, and M. szulgai was investigated by the agar gel diffusion technique using the respective absorbed antialpha serum on a total of 225 strains classified into 13 species of slowly growing mycobacteria. The specific antigenic determinants in alpha antigen of M. scrofulaceum, M. gordonae, and M. szulgai were species specific, whereas those of M. avium and M. intracellulare were M. avium-M. intracellulare complex specific. Alpha antigens were found to be stable. These results suggest that the absorbed serums of antialpha- M. avium-intracellulare, -M. scrofulaceum, -M. gordonae, and -M. szulgai are useful for serologic identification of these species of slowly growing mycobacteria.

摘要

采用琼脂凝胶扩散技术,利用各自吸收的抗α血清,对总共225株分为13种缓慢生长分枝杆菌的菌株,研究了鸟分枝杆菌、胞内分枝杆菌、瘰疬分枝杆菌、戈登分枝杆菌和苏尔加分枝杆菌α抗原中抗原决定簇的特异性。瘰疬分枝杆菌、戈登分枝杆菌和苏尔加分枝杆菌α抗原中的特异性抗原决定簇是种特异性的,而鸟分枝杆菌和胞内分枝杆菌的是鸟分枝杆菌 - 胞内分枝杆菌复合群特异性的。发现α抗原是稳定的。这些结果表明,抗α - 鸟分枝杆菌 - 胞内分枝杆菌、 - 瘰疬分枝杆菌、 - 戈登分枝杆菌和 - 苏尔加分枝杆菌的吸收血清可用于这些缓慢生长分枝杆菌种的血清学鉴定。

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