State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
Biomed Environ Sci. 2013 Sep;26(9):709-16. doi: 10.3967/0895-3988.2013.09.001.
To study the prevalence of atrial fibrillation (AF) and the relation with its risk factors in China.
A total of 19 363 participants (8635 males and 10 728 females) aged ⋝35 years in geographically dispersed urban and rural regions of China were included in this cross-sectional survey. All participants received questionnaire, physical and blood examination. Echocardiography were performed for AF patients found in the survey.
Of the 19 363 participants, 199 were diagnosed with AF. The estimated age-standardized prevalence of AF was 0.78% in men and 0.76% in women. The prevalence of AF in participants aged <60 years was 0.41% in men and 0.43% in women, and was 1.83% in both men and women aged ⋝60 years. About 19.0% of males and 30.9% of females with AF were diagnosed with valve disease. Age- and sex-adjusted multivariable logistic regression analysis revealed that myocardial infarction, left ventricular hypertrophy (LVH), obesity, and alcohol consumption were associated with a increased risk of AF(P<0.05).
The age standardized prevalence of AF is 0.77% in the participants enrolled in the present study. The number of AF cases aged ⋝35 years is 5.26 million according to 2010 Chinese Census. Most risk factors for AF, identified mainly in Western countries, are also detected in China.
研究中国心房颤动（AF）的患病率及其与危险因素的关系。
本横断面研究共纳入中国地理分布广泛的城乡地区年龄 ⋝35 岁的 19363 名参与者（8635 名男性和 10728 名女性）。所有参与者均接受问卷调查、体格检查和血液检查。对调查中发现的 AF 患者进行超声心动图检查。
在 19363 名参与者中，有 199 人被诊断为 AF。估计年龄标准化的 AF 患病率为男性 0.78%，女性 0.76%。年龄 ⋝60 岁的参与者中，AF 的患病率为男性 0.41%，女性 0.43%，而年龄 ⋝60 岁的男性和女性均为 1.83%。约 19.0%的男性和 30.9%的女性 AF 患者被诊断为瓣膜病。年龄和性别调整的多变量逻辑回归分析显示，心肌梗死、左心室肥厚（LVH）、肥胖和饮酒与 AF 风险增加相关（P<0.05）。
本研究参与者中 AF 的年龄标准化患病率为 0.77%。根据 2010 年中国人口普查，年龄 ⋝35 岁的 AF 患者人数为 526 万。在西方国家主要发现的 AF 大多数危险因素在中国也有发现。
