t(4;11)急性白血病中白血病细胞的体外培养
In vitro culture of leukemic cells in t(4;11) acute leukemia.
作者信息
Stong R C, Kersey J H
出版信息
Blood. 1985 Aug;66(2):439-43.
PMID:2410069
Abstract
In the present study we utilized a semisolid culture system with feeder cells and enriched media to evaluate the growth of acute leukemia associated with the 4;11 chromosomal translocation. We compared growth of t(4;11) leukemia to typical acute nonlymphocytic leukemia (ANL) and acute lymphocytic leukemia (ALL). The two cases of t(4;11) leukemia tested exhibited the highest cloning efficiency of cells tested. The growth characteristics of t(4;11) leukemia were more similar to ANL than ALL.
摘要
在本研究中，我们利用一种带有饲养细胞和富集培养基的半固体培养系统，来评估与4;11染色体易位相关的急性白血病的生长情况。我们将t(4;11)白血病的生长情况与典型的急性非淋巴细胞白血病（ANL）和急性淋巴细胞白血病（ALL）进行了比较。所检测的两例t(4;11)白血病病例表现出所检测细胞中最高的克隆效率。t(4;11)白血病的生长特征与ANL比与ALL更为相似。
Zotero 插件