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美国不同种族对减重手术疗效和应用的影响。

Influence of ethnicity on the efficacy and utilization of bariatric surgery in the USA.

机构信息

Duke University Medical Center, Durham, 27710, NC, USA,

出版信息

J Gastrointest Surg. 2014 Jan;18(1):130-6. doi: 10.1007/s11605-013-2368-1. Epub 2013 Oct 8.

DOI:10.1007/s11605-013-2368-1
PMID:24101449
Abstract

BACKGROUND

Ethnic disparities in patterns of utilization and outcomes after Roux-en-Y gastric bypass surgery (RYGB) were examined from Bariatric Outcomes Longitudinal Database.

METHODS

Descriptive statistics were used for demographics of Whites, Blacks, or Hispanics undergoing RYGB with 1 year of follow-up, between June 2007 and October 2011. Multivariate logistic and normal regression models, controlling for baseline characteristics, examined relationships between race and outcomes. T tests were used for continuous variables and Pearson chi-square test for categorical variables.

RESULTS

Study patients (108,333) were79 % White, 12 % Black, and 9 % Hispanic. Fewer Black males underwent surgery (15 %) compared to Whites or Hispanics (∼22 %). Blacks compared to Whites were younger (42.7 ± 10.6 vs. 46.4 ± 11.6 years), heavier BMI (50 ± 9.1 vs. 47.4 ± 8.0 kg/m(2)), and more often hypertensive (57 vs. 52 %). Other comorbidities were higher in Whites. Thirty-day mortality rate was equivalent (0.23-0.26 %), but serious adverse events were higher for Blacks (3.65 %) versus Whites (3.19 %) and Hispanics (2.01 %). At 1 year, weight and comorbidity burden declined significantly but less in Blacks despite adjustment for baseline characteristics.

CONCLUSIONS

Fewer Black males underwent RYGB. Despite a smaller percent decline in BMI and comorbidities in Blacks, all races benefitted significantly from RYGB. Influence of other factors such as diet, culture, and genetics needs to be investigated further.

摘要

背景

从减肥手术结果纵向数据库(Bariatric Outcomes Longitudinal Database)中检查了 Roux-en-Y 胃旁路手术(RYGB)后利用和结果的种族差异。

方法

对 2007 年 6 月至 2011 年 10 月期间接受 RYGB 并随访 1 年的白人、黑人和西班牙裔患者的人口统计学数据进行描述性统计。使用多元逻辑和正态回归模型,控制基线特征,检查种族与结果之间的关系。连续变量采用 t 检验,分类变量采用 Pearson 卡方检验。

结果

研究患者(108333 例)中 79%为白人,12%为黑人,9%为西班牙裔。与白人或西班牙裔相比,黑人男性接受手术的比例较少(15%)。与白人相比,黑人更年轻(42.7±10.6 岁比 46.4±11.6 岁),体重指数(BMI)更高(50±9.1 千克/平方米比 47.4±8.0 千克/平方米),且高血压的发生率更高(57%比 52%)。白人的其他合并症更高。30 天死亡率相当(0.23-0.26%),但黑人的严重不良事件发生率更高(3.65%比白人 3.19%和西班牙裔 2.01%)。尽管调整了基线特征,但 1 年后体重和合并症负担显著下降,但黑人的下降幅度较小。

结论

黑人男性接受 RYGB 的比例较低。尽管黑人的 BMI 和合并症百分比下降幅度较小,但所有种族都从 RYGB 中获益显著。需要进一步调查饮食、文化和遗传等其他因素的影响。

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