Zaric Bojan, Stojsic Vladimir, Tepavac Aleksandar, Sarcev Tatjana, Zarogoulidis Paul, Darwiche Kaid, Tsakiridis Kosmas, Karapantzos Ilias, Kesisis Georgios, Kougioumtzi Ioanna, Katsikogiannis Nikolaos, Machairiotis Nikolaos, Stylianaki Aikaterini, Foroulis Christophoros N, Zarogoulidis Konstantinos, Perin Branislav
Institute for Pulmonary Diseases of Vojvodina, Clinic for Thoracic Oncology, Faculty of Medicine, University of Novi Sad, Serbia;
J Thorac Dis. 2013 Sep;5 Suppl 4(Suppl 4):S371-7. doi: 10.3978/j.issn.2072-1439.2013.05.16.
Lung cancer is one of the most common human malignancies and remains the leading cause of cancer related deaths worldwide. Many recent technological advances led to improved diagnostics and staging of lung cancer. With development of new treatment options such as targeted therapies there might be improvement in progression free survival of patients with advanced stage non-small cell lung cancer (NSCLC). Improvement in overall survival is still reserved for selected patients and selected treatments. One of the mostly investigated therapeutic options is adjuvant treatment. There are many open issues in selection of patients and administration of appropriate adjuvant treatment.
肺癌是人类最常见的恶性肿瘤之一,仍是全球癌症相关死亡的主要原因。最近的许多技术进步使肺癌的诊断和分期得到了改善。随着靶向治疗等新治疗方案的发展,晚期非小细胞肺癌(NSCLC)患者的无进展生存期可能会有所改善。总体生存率的提高仍仅限于部分患者和特定治疗。辅助治疗是研究最多的治疗选择之一。在患者选择和适当辅助治疗的实施方面存在许多未解决的问题。