Lung Transplantation Unit, University Hospital Gasthuisberg, Leuven, Belgium.
Am J Transplant. 2013 Nov;13(11):3035-40. doi: 10.1111/ajt.12474. Epub 2013 Sep 18.
This case report describes the evolution of pulmonary function findings (FVC, FEV1 and TLC) and CT features with pirfenidone treatment for restrictive allograft syndrome following lung transplantation. Furthermore, we herein report hypermetabolic activity on (18) F-FDG PET imaging in this setting, which could indicate active fibroproliferation and pleuroparenchymal remodeling. These findings may warrant further investigation.
本病例报告描述了肺功能（FVC、FEV1 和 TLC）的演变以及 CT 特征，以及吡非尼酮治疗肺移植后限制性移植物综合征。此外，我们在此报告了这种情况下（18）F-FDG PET 成像的高代谢活性，这可能表明存在活跃的纤维增生和胸膜实质重塑。这些发现可能需要进一步研究。
