University of Florida, College of Medicine, Department of Emergency Medicine Gainesville, Florida.
West J Emerg Med. 2013 Sep;14(5):518-24. doi: 10.5811/westjem.2013.1.14693.
Early antibiotic administration is recommended in newborns presenting with febrile illness to emergency departments (ED) to avert the sequelae of serious bacterial infection. Although ED crowding has been associated with delays in antibiotic administration in a dedicated pediatric ED, the majority of children that receive emergency medical care in the United States present to EDs that treat both adult and pediatric emergencies. The purpose of this study was to examine the relationship between time to antibiotic administration in febrile newborns and crowding in a general ED serving both an adult and pediatric population.
We conducted a retrospective chart review of 159 newborns presenting to a general ED between 2005 and 2011 and analyzed the association between time to antibiotic administration and ED occupancy rate at the time of, prior to, and following infant presentation to the ED.
We observed delayed and variable time to antibiotic administration and found no association between time to antibiotic administration and occupancy rate prior to, at the time of, or following infant presentation (p>0.05). ED time to antibiotic administration was not associated with hospital length of stay, and there was no inpatient mortality.
Delayed and highly variable time to antibiotic treatment in febrile newborns was common but unrelated to ED crowding in the general ED study site. Guidelines for time to antibiotic administration in this population may reduce variability in ED practice patterns.
建议在有发热症状的新生儿到急诊部(ED)就诊时尽早使用抗生素,以避免严重细菌感染的后遗症。尽管在专门的儿科 ED 中,ED 拥挤与抗生素给药延迟有关,但在美国接受紧急医疗护理的大多数儿童都到同时治疗成人和儿科急症的 ED 就诊。本研究的目的是研究在同时治疗成人和儿科急症的普通 ED 中,发热新生儿抗生素给药时间与拥挤之间的关系。
我们对 2005 年至 2011 年间在普通 ED 就诊的 159 名新生儿进行了回顾性图表审查,并分析了抗生素给药时间与 ED 入住率在婴儿就诊前、就诊时和就诊后之间的关系。
我们观察到抗生素给药时间延迟且变化较大,但未发现抗生素给药时间与婴儿就诊前、就诊时或就诊后入住率之间存在关联(p>0.05)。ED 抗生素给药时间与住院时间长短无关,也没有住院患者死亡。
在普通 ED 研究现场,发热新生儿抗生素治疗时间延迟且高度可变,但与 ED 拥挤无关。该人群抗生素给药时间的指南可能会减少 ED 实践模式的变异性。