The Clinical Research Unit for Anxiety and Depression, School of Psychiatry, The University of New South Wales, Level 4 O'Brien Building at St, Vincent's Hospital, Sydney, Australia.
BMC Psychiatry. 2013 Oct 9;13:256. doi: 10.1186/1471-244X-13-256.
Cognitive bias modification (CBM) protocols have been developed to help establish the causal role of biased cognitive processing in maintaining psychopathology and have demonstrated therapeutic benefits in a range of disorders. The current study evaluated a cognitive bias modification training paradigm designed to target interpretation biases (CBM-I) associated with obsessive compulsive disorder (OCD).
We evaluated the impact of CBM-I on measures of interpretation bias, distress, and on responses to three OC stressor tasks designed to tap the core belief domains of Importance of Thoughts/Control, Perfectionism/Intolerance of Uncertainty, and Contamination/Estimation of Threat in a selected sample of community members reporting obsessive compulsive (OC) symptoms (N = 89).
Participants randomly assigned to the Positive condition evidenced a change in interpretation bias towards more positive and less negative OC-relevant interpretations following CBM-I compared to participants assigned to the Control condition. Importantly, a positivity bias was not observed for foil scenarios unrelated to the core OC belief domains. Further, participants in the Positive condition reported less distress and urge to neutralize following an OC stressor task designed to tap Importance of Thoughts/Control. No significant difference emerged on the indices of behavioural response to the OC stressor tasks. Severity of OC symptoms did not moderate the effects of positive CBM-I training.
CBM-I appears effective in selectively targeting OC beliefs. Results need to be replicated in clinical samples in order for potential therapeutic benefit to be demonstrated.
认知偏差修正（CBM）方案旨在帮助确定有偏差的认知处理在维持精神病理学中的因果作用，并已在一系列障碍中显示出治疗益处。本研究评估了一种旨在针对与强迫症（OCD）相关的解释偏差（CBM-I）的认知偏差修正训练方案。
我们评估了 CBM-I 对解释偏差、痛苦的测量的影响，以及对三个 OC 应激任务的反应，这些任务旨在挖掘强迫症核心信念领域的重要性/思考控制、完美主义/不确定性不容忍和污染/威胁估计，在报告强迫症（OC）症状的社区成员中选择了一组样本（N = 89）。
与分配到对照组的参与者相比，随机分配到阳性条件的参与者在接受 CBM-I 后，对与 OC 相关的解释表现出更积极、更消极的解释偏差变化。重要的是，对于与核心 OC 信念领域无关的箔片情景，没有观察到积极偏见。此外，在旨在挖掘思想/控制重要性的 OC 应激任务后，阳性条件的参与者报告的痛苦和中立化冲动较少。在 OC 应激任务的行为反应指标上没有出现显著差异。OC 症状的严重程度没有调节积极 CBM-I 训练的效果。
CBM-I 似乎可以有效地针对 OC 信念。为了证明潜在的治疗益处，需要在临床样本中复制结果。
