The Center for Alcohol & Addiction Studies, Brown University, USA.
J Behav Ther Exp Psychiatry. 2011 Sep;42(3):337-43. doi: 10.1016/j.jbtep.2011.01.003. Epub 2011 Jan 12.
The current study tested the causal premise underlying cognitive models of obsessive compulsive disorder (OCD) that negative interpretations of intrusive thoughts lead to the distress and impairment associated with symptoms of OCD. Specifically, we sought to determine: (a) whether it was possible to train healthier (defined as more benign/less threatening) interpretations regarding the significance of intrusive thoughts; and (b) whether there was a link between modifying negative interpretations and subsequent emotional vulnerability to an OC stressor. A nonclinical sample of students high in OC symptoms completed either a Positive (n = 50) or Neutral (n = 50) interpretation training procedure designed to alter OC-relevant interpretations and beliefs. As expected, participants in the Positive (versus Neutral) training condition endorsed healthier OC-relevant interpretations and beliefs following training. Additionally, when controlling for baseline affect, participants in the Positive (versus Neutral) training condition reported less negative affect during the OC-stressor task (at the level of a non-significant trend) and reported less desire to perform neutralizing activities. In general, results provide some support for cognitive models of obsessions and suggest that negative interpretations of intrusive thoughts may be causally related to symptoms of OCD.
本研究旨在检验强迫症（OCD）认知模型的一个因果前提，即对侵入性思维的负面解读会导致与 OCD 症状相关的痛苦和障碍。具体而言，我们试图确定：(a) 是否有可能对侵入性思维的意义进行更健康（定义为更良性/威胁性较小）的解读；以及 (b) 改变负面解读与随后对 OC 应激源的情绪脆弱性之间是否存在关联。一组 OC 症状较高的非临床学生样本完成了积极（n=50）或中性（n=50）的解释训练程序，旨在改变与 OC 相关的解释和信念。正如预期的那样，与中性训练条件相比，积极训练条件下的参与者在训练后更倾向于接受更健康的 OC 相关解释和信念。此外，在控制基线情绪的情况下，与中性训练条件相比，积极训练条件下的参与者在 OC 应激任务期间报告的负面情绪较少（存在非显著趋势），并报告较少进行中性化活动的欲望。总的来说，研究结果为强迫症的认知模型提供了一些支持，并表明对侵入性思维的负面解读可能与 OCD 症状存在因果关系。
