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[急性肺炎患儿循环免疫复合物及补体水平]

[Circulating immune complexes and the complement level in children with acute pneumonia].

作者信息

Popova O Ia, Rodshteĭn O A, Kositskaia L S, Shteĭnlukht P L

出版信息

Ter Arkh. 1985;57(5):42-5.

PMID:2410992
Abstract

It has been shown that study of immunopathological component in acute pneumonias is of value. Such an approach has demonstrated that in the course of the disease there form immune complexes (IC), which absorb complement and are of importance for the disease pathogenesis, and tissue immune complexes which do not absorb complement. Formation of anticomplement IC in acute pneumonias is in a good agreement with a reduction in blood serum complement level with a concurrent change in these indicators in the lungs. The demonstration of anticomplement IC in patients with acute pneumonia has a prognostic value. The stay at hospital of the patients who demonstrated IC at the very beginning of the disease was 2.5 times longer because of the lack of the process normalization.

摘要

已经表明,对急性肺炎免疫病理成分的研究具有重要意义。这种方法已经证明,在疾病过程中会形成免疫复合物(IC),其可吸收补体,对疾病发病机制具有重要意义,还有不吸收补体的组织免疫复合物。急性肺炎中抗补体IC的形成与血清补体水平降低以及肺部这些指标的同时变化高度一致。急性肺炎患者中抗补体IC的证实具有预后价值。由于病情缺乏正常化,在疾病一开始就显示出IC的患者住院时间延长了2.5倍。

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