Chen Hung-Nien, Chen Guan-Ming, Lin Bo-Sian, Lien Pi-Hsien, Chen Yung-Yaw, Chen Gin-Shin, Lin Win-Li
Annu Int Conf IEEE Eng Med Biol Soc. 2013;2013:3726-8. doi: 10.1109/EMBC.2013.6610353.
Therapeutic ultrasound transducers can carry out precise and efficient power deposition for tumor thermal therapy under the guidance of magnetic resonance imaging. For a better heating, organ-specific ultrasound transducers with precision location control system should be developed for tumors located at various organs. It is feasible to perform a better heating for breast tumor thermal therapy with a ring-shaped ultrasound phased-array transducer. In this study, we developed ring-shaped phased-array ultrasound transducers with 1.0 and 2.5 MHz and a precision location control system to drive the transducers to the desired location to sonicate the designated region. Both thermo-sensitive hydrogel phantom and ex vivo fresh pork were used to evaluate the heating performance of the transducers. The results showed that the ring-shaped phased array ultrasound transducers were very promising for breast tumor heating with the variation of heating patterns and without overheating the ribs.
治疗性超声换能器可在磁共振成像引导下，为肿瘤热疗进行精确且高效的能量沉积。为实现更好的加热效果，对于位于不同器官的肿瘤，应开发具备精确位置控制系统的器官特异性超声换能器。使用环形超声相控阵换能器对乳腺肿瘤热疗进行更好的加热是可行的。在本研究中，我们开发了1.0和2.5兆赫的环形相控阵超声换能器以及一个精确位置控制系统，以驱动换能器至期望位置，从而对指定区域进行超声处理。热敏水凝胶体模和离体新鲜猪肉均被用于评估换能器的加热性能。结果表明，环形相控阵超声换能器在乳腺肿瘤加热方面极具前景，其加热模式多样，且不会使肋骨过热。
