Yamashita M, Miyata S, Takeuchi S, Inoue H
Annu Int Conf IEEE Eng Med Biol Soc. 2013;2013:4462-5. doi: 10.1109/EMBC.2013.6610537.
Platelet Rich Plasma (PRP) contains many cytokines for treatment skin diseases. The final goal of this study is to develop the dielectrophoretic PRP purification system enriching the platelets in a label-free manner from whole blood solution. In this study, we characterized dielectrophoretic properties of red blood cell, white blood cell, and platelet for the fundamental study. Moreover, purification of PRP was performed to eliminate red and white blood cells using dielectrophoretic and flow-induced shear force.
富血小板血浆(PRP)含有多种用于治疗皮肤疾病的细胞因子。本研究的最终目标是开发一种介电泳PRP纯化系统,以无标记方式从全血溶液中富集血小板。在本研究中,为了进行基础研究,我们对红细胞、白细胞和血小板的介电泳特性进行了表征。此外,利用介电泳和流动诱导剪切力对PRP进行纯化,以去除红细胞和白细胞。