Alam Mumtaz, Iqbal Mustafa, Khan Bakht Samar, Hussain Ibrar
Department of Ophthalmology, Eye 'B' Unit, Khyber Teaching Hospital, Peshawar.
J Coll Physicians Surg Pak. 2013 Oct;23(10):740-2. doi: 10.2013/JCPSP.740742.
Vogt Koyanagi Harada (VKH) disease is a chronic, bilateral, granulomatous panuveitis associated with central nervous system, auditory and integumentary manifestations. The study was conducted from January 2001 to December 2010 at the Department of Ophthalmology, Khyber Teaching Hospital, Peshawar. A total of 9 patients with diagnosis of Vogt Koyanagi Harada disease were included in the study. Extracted data included age, gender, duration of disease, initial and final visual acuities, treatment and complications. Initial visual acuity was ranging from 6/24 to perception of light. All the patients were treated with systemic and topical corticosteroids. In addition, one patient also received cytotoxic therapy. Final visual acuity was 6/18 or better in all cases (100%). One patient developed bilateral cataract, glaucoma and subretinal fibrosis at the macula. The cataract and glaucoma were managed as per established protocols. The visual prognosis of Vogt Koyanagi Harada disease is generally favourable if the disease is identified early and adequately treated and the associated complications are addressed properly.
伏格特-小柳-原田（VKH）病是一种慢性、双侧性、肉芽肿性全葡萄膜炎，伴有中枢神经系统、听觉及皮肤表现。该研究于2001年1月至2010年12月在白沙瓦开伯尔教学医院眼科进行。共有9例诊断为伏格特-小柳-原田病的患者纳入该研究。提取的数据包括年龄、性别、病程、初始及最终视力、治疗及并发症。初始视力范围为6/24至光感。所有患者均接受全身及局部皮质类固醇治疗。此外，1例患者还接受了细胞毒性疗法。所有病例（100%）的最终视力均为6/18或更好。1例患者出现双侧白内障、青光眼及黄斑部视网膜下纤维化。白内障和青光眼按照既定方案进行处理。如果能早期识别并充分治疗伏格特-小柳-原田病，并妥善处理相关并发症，其视觉预后通常较好。
