Schmitt Kai-Uwe, Lanz Christian, Muser Markus H, Walz Felix, Schwarz Urs
AGU - Working Group on Accident Mechanics, Winkelriedstrasse 27, CH 8006 Zurich, Switzerland; Institute for Biomedical Engineering, University and ETH Zurich, Gloriastrasse 35, CH 8092 Zurich, Switzerland.
J Forensic Leg Med. 2013 Oct;20(7):870-4. doi: 10.1016/j.jflm.2013.06.023. Epub 2013 Aug 13.
The influence of low-dose alcohol intake on reflexive visually guided saccades was investigated.
40 healthy human subjects were orally given alcohol resulting in low-dose alcohol concentration (less than 0.8‰) blood alcohol concentration. Before and after exposure, horizontal saccadic eye movements were recorded at several points in time. The recordings were evaluated with regard to accuracy of the eye movements, latency, the peak eye velocity and the time constant that characterizes the main sequence. The results were compared to recordings from a reference group.
It was found that the saccadic eye movement was clearly altered by low-dose alcohol intake. However, its characteristics were not unambiguously pathological when compared to the reference group, even though the subjects reported a moderate to strong effect of alcohol and there were clear signs of inebriation.
The findings render the evaluation of saccades unsuitable as a simple test for the detection of low-dose alcohol intake.
研究低剂量酒精摄入对反射性视觉引导扫视的影响。
40名健康受试者口服酒精，使血液酒精浓度达到低剂量酒精浓度（低于0.8‰）。在接触酒精前后的几个时间点记录水平扫视眼动。对记录结果进行评估，包括眼动准确性、潜伏期、眼峰值速度以及表征主序列的时间常数。将结果与对照组的记录进行比较。
发现低剂量酒精摄入明显改变了扫视眼动。然而，与对照组相比，其特征并非明确的病理性，尽管受试者报告有中度至强烈的酒精效应且有明显的醉酒迹象。
这些发现表明，扫视评估不适用于作为检测低剂量酒精摄入的简单测试。
