利用学习技术对原核生物信使核糖核酸中翻译起始位点进行定位。
Localization of the initiation of translation in messenger RNAs of prokaryotes by learning techniques.
作者信息
Rodier F, Sallantin J
出版信息
Biochimie. 1985 May;67(5):533-9. doi: 10.1016/s0300-9084(85)80273-x.
PMID:2411301
Abstract
Learning processes are applied to the recognition of protein coding regions in prokaryotes. Non-contradictory, statistical and logical rules are deduced from a set of known examples of coding sequences. These rules enable to build characteristic patterns on the m-RNA upstream of the initiating codon. These rules are applied with success to recognize more than 180 coding sequences and to detect and/or eliminate hypothetical reading frames or unknown genes.
摘要
学习过程被应用于原核生物中蛋白质编码区域的识别。从一组已知的编码序列示例中推导出不矛盾、统计和逻辑规则。这些规则能够在起始密码子上游的mRNA上构建特征模式。这些规则成功应用于识别超过180个编码序列，并检测和/或消除假设的阅读框或未知基因。
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