Nagaratnam N, Vitarana U T, Alagaratnam K, Thambapillai A J, Fernando D C
Trop Geogr Med. 1975 Jun;27(2):177-80.
Twenty-four out of 72 sera from patients with acute viral hepatitis were positive for HB Ag. HB Ag positive males were more severely ill than HB Ag positive females. The sera of four patients with active chronic hepatitis were negative for HB Ag. Thirteen sera of HB Ag positive cases were tested for anti-nuclear factor, all with negative results. In all four patients with active chronic hepatitis anti-nuclear factor was positive. There was a high incidence of latex fixation reactivity in the HB Ag positive cases (9 out of 13). Arbovirus antibodies were detected in 16 out of 18 HB Ag positive cases and in 19 out of 27 HB Ag negative cases of acture viral hepatitis. Fifty percent of these HB Ag positive cases had titers suggestive of recent infection as against 33% of the HB Ag negative cases. The arbovirus antibody titers were determined in four out of six HB Ag positive cases that did not give a history of parenteral injections and in everyone of them the titers were suggestive of a recent arbovirus infection.
72例急性病毒性肝炎患者的血清中，有24例HB抗原呈阳性。HB抗原阳性的男性患者病情比HB抗原阳性的女性患者更严重。4例活动性慢性肝炎患者的血清HB抗原呈阴性。对13例HB抗原阳性病例的血清进行了抗核因子检测，结果均为阴性。所有4例活动性慢性肝炎患者的抗核因子均为阳性。HB抗原阳性病例中乳胶凝集反应的发生率很高（13例中有9例）。在18例HB抗原阳性的急性病毒性肝炎病例中，有16例检测到虫媒病毒抗体；在27例HB抗原阴性的急性病毒性肝炎病例中，有19例检测到虫媒病毒抗体。这些HB抗原阳性病例中有50%的滴度提示近期感染，而HB抗原阴性病例中这一比例为33%。在6例无肠道外注射史的HB抗原阳性病例中，有4例测定了虫媒病毒抗体滴度，其中每一例的滴度都提示近期有虫媒病毒感染。
