Department of Chemistry, Humboldt-University Berlin, Brook-Taylor Strasse 2, 12489 Berlin (Germany).
Chemistry. 2013 Oct 18;19(43):14346-96. doi: 10.1002/chem.201301996. Epub 2013 Sep 20.
Beyond a doubt organocatalysis belongs to the most exciting and innovative chapters of organic chemistry today. Organocatalysis has emerged not only as a complement to metal-catalyzed reactions and to biocatalysis over the last decade, but also provides new asymmetric organocatalyzed reactions that cannot be accomplished by metal- or biocatalyzed reactions so far. A large number of organocatalytic processes are already well established in organic synthesis. Nevertheless, the number of publications in this field is still on the increase; new important results are produced constantly. This review gives a detailed overview of the latest developments and main streams in organocatalyzed asymmetric CC bond formation processes of the last three years. It is intended to outline the most important current findings focused on especially new synthetic methodologies.
毫无疑问，有机催化属于当今有机化学最令人兴奋和创新的领域之一。在过去十年中，有机催化不仅作为金属催化反应和生物催化的补充出现，而且还提供了新的不对称有机催化反应，迄今为止，这些反应无法通过金属或生物催化反应来完成。大量的有机催化过程已经在有机合成中得到很好的确立。然而，该领域的出版物数量仍在增加；新的重要成果不断涌现。本文综述了过去三年中有机催化不对称 C-C 键形成过程的最新发展和主要趋势，旨在概述当前最重要的发现，特别是新的合成方法学。
