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Acquired factor V deficiency in a patient without evidence of a classical inhibitor.

作者信息

Sosa I R, Ellery P, Mast A, Neff A T, Gailani D

机构信息

Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Division of Hematology and Oncology, Vanderbilt University Medical Center, Nashville, TN, USA.

出版信息

Haemophilia. 2014 Jan;20(1):e81-3. doi: 10.1111/hae.12280. Epub 2013 Oct 14.

DOI:10.1111/hae.12280
PMID:24118596
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3870044/
Abstract
摘要

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Maintaining extraembryonic expression allows generation of mice with severe tissue factor pathway inhibitor deficiency.维持胚外组织表达可产生组织因子途径抑制物严重缺乏的小鼠。
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本文引用的文献

1
Tissue factor pathway inhibitor: structure-function.组织因子途径抑制剂:结构-功能。
Front Biosci (Landmark Ed). 2012 Jan 1;17(1):262-80. doi: 10.2741/3926.
2
Inherited and acquired factor V deficiency.遗传性和获得性因子V缺乏症。
Blood Coagul Fibrinolysis. 2011 Apr;22(3):160-6. doi: 10.1097/MBC.0b013e3283424883.
3
Acquired factor V inhibitors: a systematic review.获得性因子 V 抑制剂:系统评价。
J Thromb Thrombolysis. 2011 May;31(4):449-57. doi: 10.1007/s11239-010-0529-6.
4
Residual platelet factor V ensures thrombin generation in patients with severe congenital factor V deficiency and mild bleeding symptoms.严重先天性因子 V 缺乏症伴轻度出血症状患者中残留的血小板因子 V 可确保凝血酶生成。
Blood. 2010 Jan 28;115(4):879-86. doi: 10.1182/blood-2009-08-237719. Epub 2009 Oct 27.
5
Advances in understanding the bleeding diathesis in factor V deficiency.凝血因子V缺乏症出血素质认识的进展
Br J Haematol. 2009 Jun;146(1):17-26. doi: 10.1111/j.1365-2141.2009.07708.x. Epub 2009 Apr 27.
6
Low plasma levels of tissue factor pathway inhibitor in patients with congenital factor V deficiency.先天性因子V缺乏症患者血浆组织因子途径抑制物水平较低。
Blood. 2008 Nov 1;112(9):3615-23. doi: 10.1182/blood-2008-06-162453. Epub 2008 Aug 11.
7
Endogenous factor V synthesis in megakaryocytes contributes negligibly to the platelet factor V pool.巨核细胞中内源性因子V的合成对血小板因子V池的贡献可忽略不计。
Haematologica. 2003 Oct;88(10):1150-6.
8
Life-threatening bleeding and acquired factor V deficiency associated with primary systemic amyloidosis.危及生命的出血与原发性系统性淀粉样变性相关的获得性凝血因子V缺乏症。
Blood Coagul Fibrinolysis. 2002 Sep;13(6):555-9. doi: 10.1097/00001721-200209000-00011.
9
Factor-X deficiency in amyloidosis: a critical review.
Am J Hematol. 1981 Dec;11(4):443-50. doi: 10.1002/ajh.2830110414.