Andreen M, Irestedt L, Thulin L
Acta Anaesthesiol Scand. 1975;19(3):238-44. doi: 10.1111/j.1399-6576.1975.tb05245.x.
The influence of halothane ansesthesia on splanchnic oxygen flow and oxygen uptake was studied in seven dogs. Mean oxygen supply to the liver and the portally-drained tissues decreased significantly to 44% and 53% of control values, respectively, while mena oxygen consumption diminished insignificantly to 68% and 82% of control values, respectively. There was a fall in the oxygen flow/oxygen consumption ratio in all animals following halothane. The relatively unimpaired oxygen uptake, in spite of a diminished oxygen supply, led to an increased extraction of oxygen by the tissues. Some factors affecting oxygen utilisation during halothane anaesthesia are discussed.
在七只狗身上研究了氟烷麻醉对内脏氧流量和氧摄取的影响。肝脏和门静脉引流组织的平均氧供应分别显著下降至对照值的44%和53%，而平均氧消耗分别无显著下降至对照值的68%和82%。氟烷麻醉后，所有动物的氧流量/氧消耗比值均下降。尽管氧供应减少，但氧摄取相对未受损害，导致组织对氧的摄取增加。讨论了氟烷麻醉期间影响氧利用的一些因素。
