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[慢性血液透析患者血清α2球蛋白和免疫球蛋白水平的月度变化——特别提及癌症的发生和输血情况]

[Monthly changes in serum alpha 2-globulin and immunoglobulin levels in chronic hemodialysis patients--with special reference to the occurrence of cancer and blood transfusion].

作者信息

Misao A, Saji S, Hosono Y, Takekoshi T, Tanaka S, Sato Y, Mori N, Yasui S, Kuriyama I

出版信息

Gan No Rinsho. 1985 Jul;31(8):953-8.

PMID:2411969
Abstract

Thirty-eight patients with chronic renal failure who were treated by hemodialysis more than 100 times each, including 13 cancer patients, were examined for serum alpha 2-globulin and immunoglobulin values monthly, the relationship between the possibility of cancer occurrence and the frequency of blood transfusion during hemodialysis was discussed. The alpha 2-globulin value of the patients treated with blood transfusion more than 20 times was significantly higher than that of the patients not receiving blood transfusion. Moreover, the IgA value was reduced and the IgM value was increased. The IgA values of cancer patients found before or during hemodialysis were significantly higher than those of patients without cancer. There was no significant difference between the group who had undergone hemodialysis more than 500 times those who had received it less than 500 times.

摘要

对38例接受血液透析100次以上的慢性肾衰竭患者(其中包括13例癌症患者)每月检测血清α2球蛋白和免疫球蛋白值,并探讨了血液透析期间癌症发生可能性与输血频率之间的关系。输血20次以上患者的α2球蛋白值显著高于未输血患者。此外,IgA值降低,IgM值升高。血液透析前或透析期间发现的癌症患者的IgA值显著高于无癌症患者。血液透析500次以上组与不足500次组之间无显著差异。

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