Li Qing-xiang, Zhang Ying, Wang Mei, Zhu Xiao-ling
The 35th Wards, Anzhen Hospital, Capital Medical University and Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing 100029, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2013 Jun;34(6):626-9.
The purpose of this research project was to evaluate the relationship and risk factors between coronary artery disease and carotid artery stenosis(CAS), screened by duplex ultra-sonography.
1339 patients with coronary artery disease were enrolled into this study. All patients performed carotid duplex ultra-sonography during hospitalization after coronary artery angiography.
The overall incidence of CAS was 11.8%(158/1339). Patients under older age and having history of stroke, the incidence rates were higher than other groups(P < 0.01, P = 0.02). The incidence of CAS in patients with multi-vessel lesions was higher than those of diseases involved in one vessel(χ(2) = 37.482, P < 0.01). CAS patients having left side major diseases, the incidence was higher than those of others(χ(2) = 38.93, P < 0.01). By multivariable logistic regression analysis, factors as:older age, having had history of stroke, with left side major disease and multivessel lesions etc. appeared to be independent predictors of CAS, respectively.
Patients with coronary artery diseases had higher prevalence rates for CAS when suffering from multi-vessel lesions or stenosis of left major stem. Factors as being elderly, having history of cerebro-vascular diseases were independent predictors of CAS in patients with coronary artery diseases.
本研究项目旨在评估经双功超声筛查的冠状动脉疾病与颈动脉狭窄（CAS）之间的关系及危险因素。
1339例冠状动脉疾病患者纳入本研究。所有患者在冠状动脉造影术后住院期间均接受了颈动脉双功超声检查。
CAS的总体发生率为11.8%（158/1339）。年龄较大及有中风病史的患者，发生率高于其他组（P<0.01，P = 0.02）。多支血管病变患者的CAS发生率高于单支血管病变患者（χ(2)=37.482，P<0.01）。左侧主要血管病变的CAS患者，发生率高于其他患者（χ(2)=38.93，P<0.01）。多因素logistic回归分析显示，年龄较大、有中风病史、左侧主要血管病变及多支血管病变等因素分别为CAS的独立预测因素。
冠状动脉疾病患者在有多支血管病变或左主干狭窄时CAS患病率较高。年龄较大、有脑血管疾病史等因素是冠状动脉疾病患者CAS的独立预测因素。
