Kawashima Takeshi, Takeuchi Takeshi, Koyanagi Ryo, Kinoshita Shigeharu, Endo Hirotoshi, Endo Kazuyoshi
1 Marine Genomics Unit, Okinawa Institute of Science and Technology Graduate University, Onna, Okinawa 904-0495, Japan.
Zoolog Sci. 2013 Oct;30(10):794-6. doi: 10.2108/zsj.30.794.
The genome sequence of the Japanese pearl oyster, the first draft genome from a mollusk, was published in February 2012. In order to curate the draft genome assemblies and annotate the predicted gene models, two annotation Jamborees were held in Okinawa and Tokyo. To date, 761 genes have been surveyed and curated. A preparatory meeting and a debriefing were held at the Misaki Marine Biological Station before and after the Jamborees. These four events, in conjunction with the sequence-decoding project, have facilitated the first series of gene annotations. Genome annotators among the Jamboree participants added 22 functional categories to the annotation system to date. Of these, 17 are included in Generic Gene Ontology. The other five categories are specific to molluskan biology, such as "Byssus Formation" and "Shell Formation", including Biomineralization and Acidic Proteins. A total of 731 genes from our latest version of gene models are annotated and classified into these 22 categories. The resulting data will serve as a useful reference for future genomic analyses of this species as well as comparative analyses among mollusks.
2012年2月发布了日本珍珠贝的基因组序列，这是来自软体动物的首个基因组草图。为了整理基因组草图组装并注释预测的基因模型，在冲绳和东京举办了两次注释研讨会。截至目前，已对761个基因进行了调查和整理。在研讨会前后，在三崎海洋生物站召开了筹备会议和总结会议。这四项活动与序列解码项目一起，推动了首批基因注释工作。研讨会参与者中的基因组注释人员迄今已在注释系统中增加了22个功能类别。其中，17个类别包含在通用基因本体中。另外五个类别是软体动物生物学特有的，如“足丝形成”和“贝壳形成”，包括生物矿化和酸性蛋白。我们最新版本的基因模型中的731个基因被注释并分类到这22个类别中。所得数据将为该物种未来的基因组分析以及软体动物之间的比较分析提供有用的参考。
