• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Antivirulence therapy for animal production: filling an arsenal with novel weapons for sustainable disease control.

作者信息

Defoirdt Tom

机构信息

Laboratory of Aquaculture and Artemia Reference Center, Ghent University, Ghent, Belgium ; Laboratory of Microbial Ecology and Technology, Ghent University, Ghent, Belgium.

出版信息

PLoS Pathog. 2013;9(10):e1003603. doi: 10.1371/journal.ppat.1003603. Epub 2013 Oct 10.

DOI:10.1371/journal.ppat.1003603
PMID:24130477
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3795005/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afae/3795005/c477de9673ad/ppat.1003603.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afae/3795005/c477de9673ad/ppat.1003603.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afae/3795005/c477de9673ad/ppat.1003603.g001.jpg

相似文献

1
Antivirulence therapy for animal production: filling an arsenal with novel weapons for sustainable disease control.用于动物生产的抗毒力疗法:为可持续疾病控制配备新型武器充实武器库。
PLoS Pathog. 2013;9(10):e1003603. doi: 10.1371/journal.ppat.1003603. Epub 2013 Oct 10.
2
Leukotoxins.白细胞毒素。
Toxins (Basel). 2020 Apr 7;12(4):231. doi: 10.3390/toxins12040231.
3
Roles of bacterial membrane vesicles.细菌膜泡的作用。
Arch Microbiol. 2015 Jan;197(1):1-10. doi: 10.1007/s00203-014-1042-7. Epub 2014 Oct 8.
4
Type III secretion systems and disease.III型分泌系统与疾病
Clin Microbiol Rev. 2007 Oct;20(4):535-49. doi: 10.1128/CMR.00013-07.
5
Prospects for the development and use of gram-negative bacterial virulence protein secretion inhibitors for prophylaxis and treatment of infectious diseases.革兰氏阴性菌毒力蛋白分泌抑制剂用于预防和治疗传染病的开发与应用前景。
Crit Rev Immunol. 2010;30(1):69-77. doi: 10.1615/critrevimmunol.v30.i1.50.
6
Establishing order for type III secretion substrates--a hierarchical process.建立III型分泌底物的顺序——一个分级过程。
Trends Microbiol. 2003 Aug;11(8):398-403. doi: 10.1016/s0966-842x(03)00155-0.
7
Extracellular proteases and possible disease related virulence mechanisms of two marine bacteria implicated in an opportunistic bacterial infection of Nephrops norvegicus.与挪威龙虾机会性细菌感染有关的两种海洋细菌的胞外蛋白酶及可能的疾病相关毒力机制
J Invertebr Pathol. 2008 Sep;99(1):14-9. doi: 10.1016/j.jip.2008.05.007. Epub 2008 Jul 9.
8
Antibodies and immune effectors: shaping Gram-negative bacterial phenotypes.抗体和免疫效应物:塑造革兰氏阴性细菌表型。
Trends Microbiol. 2010 Jun;18(6):234-9. doi: 10.1016/j.tim.2010.03.001. Epub 2010 Mar 30.
9
Gram-negative bacterial protein secretion.革兰氏阴性菌的蛋白质分泌
J Infect. 2000 Mar;40(2):121-6. doi: 10.1016/s0163-4453(00)80002-x.
10
Mechanisms of protein export across the bacterial outer membrane.蛋白质跨细菌外膜输出的机制。
J Bacteriol. 2005 Jul;187(13):4306-14. doi: 10.1128/JB.187.13.4306-4314.2005.

引用本文的文献

1
Quercetin and Silybin Decrease Intracellular Replication of in SHK-1 Cell.槲皮素和水飞蓟宾减少SHK-1细胞中[病原体名称未给出]的细胞内复制。
Int J Mol Sci. 2025 Jan 29;26(3):1184. doi: 10.3390/ijms26031184.
2
Design, Synthesis, and Biological Evaluation of the Quorum-Sensing Inhibitors of PAO1.PAO1 群体感应抑制剂的设计、合成与生物评价。
Molecules. 2024 May 8;29(10):2211. doi: 10.3390/molecules29102211.
3
Medicinal Chemistry of Inhibitors Targeting Resistant Bacteria.靶向耐药细菌的抑制剂的药物化学

本文引用的文献

1
Synthesis and evaluation of thiazolidinedione and dioxazaborocane analogues as inhibitors of AI-2 quorum sensing in Vibrio harveyi.噻唑烷二酮和二氧杂硼烷类似物的合成与评价及其作为 Harvey 弧菌 AI-2 群体感应抑制剂的研究。
Bioorg Med Chem. 2013 Feb 1;21(3):660-7. doi: 10.1016/j.bmc.2012.11.055. Epub 2012 Dec 11.
2
Pathogen espionage: multiple bacterial adrenergic sensors eavesdrop on host communication systems.病原体谍报:多种细菌肾上腺素传感器窃听宿主通讯系统。
Mol Microbiol. 2013 Feb;87(3):455-65. doi: 10.1111/mmi.12110. Epub 2012 Dec 11.
3
Quorum sensing inhibitors: an overview.
Curr Top Med Chem. 2022;22(24):1983-2028. doi: 10.2174/1568026622666220321124452.
4
spp. Inhibit Quorum-Sensing and Fish Infection. spp. 抑制群体感应和鱼类感染。
Mar Drugs. 2021 Oct 23;19(11):602. doi: 10.3390/md19110602.
5
QseC Inhibition as a Novel Antivirulence Strategy for the Prevention of Acute Hepatopancreatic Necrosis Disease (AHPND)-Causing .抑制QseC作为预防由急性肝胰腺坏死病(AHPND)引起疾病的一种新型抗毒力策略
Front Cell Infect Microbiol. 2021 Jan 21;10:594652. doi: 10.3389/fcimb.2020.594652. eCollection 2020.
6
Novel Treatments and Preventative Strategies Against Food-Poisoning Caused by Staphylococcal Species.针对葡萄球菌属引起的食物中毒的新型治疗方法和预防策略。
Pathogens. 2021 Jan 20;10(2):91. doi: 10.3390/pathogens10020091.
7
Virulence-inhibitory activity of the degradation product 3-hydroxybutyrate explains the protective effect of poly-β-hydroxybutyrate against the major aquaculture pathogen Vibrio campbellii.降解产物 3-羟基丁酸的毒力抑制活性解释了聚-β-羟基丁酸对水产养殖主要病原体坎贝尔弧菌的保护作用。
Sci Rep. 2018 May 8;8(1):7245. doi: 10.1038/s41598-018-25385-w.
8
Specific quorum sensing-disrupting activity (A QSI) of thiophenones and their therapeutic potential.噻吩酮类化合物的特定群体感应干扰活性(A QSI)及其治疗潜力。
Sci Rep. 2015 Dec 9;5:18033. doi: 10.1038/srep18033.
9
Tea polyphenols as an antivirulence compound Disrupt Quorum-Sensing Regulated Pathogenicity of Pseudomonas aeruginosa.茶多酚作为一种抗毒力化合物破坏铜绿假单胞菌群体感应调节的致病性。
Sci Rep. 2015 Nov 9;5:16158. doi: 10.1038/srep16158.
10
Interaction of Vibrio spp. with the Inner Surface of the Digestive Tract of Penaeus monodon.弧菌属与斑节对虾消化道内表面的相互作用。
PLoS One. 2015 Aug 18;10(8):e0135783. doi: 10.1371/journal.pone.0135783. eCollection 2015.
群体感应抑制剂:概述。
Biotechnol Adv. 2013 Mar-Apr;31(2):224-45. doi: 10.1016/j.biotechadv.2012.10.004. Epub 2012 Nov 9.
4
The luxS gene functions in the pathogenesis of avian pathogenic Escherichia coli.luxS 基因在禽致病性大肠杆菌的发病机制中起作用。
Microb Pathog. 2013 Feb;55:21-7. doi: 10.1016/j.micpath.2012.09.008. Epub 2012 Oct 6.
5
A quorum sensing-disrupting brominated thiophenone with a promising therapeutic potential to treat luminescent vibriosis.一种具有治疗发光弧菌病潜力的群体感应扰乱溴化噻吩酮。
PLoS One. 2012;7(7):e41788. doi: 10.1371/journal.pone.0041788. Epub 2012 Jul 25.
6
Monitoring of Vibrio harveyi quorum sensing activity in real time during infection of brine shrimp larvae.实时监测哈维弧菌群体感应活性在卤虫幼虫感染过程中的变化。
ISME J. 2012 Dec;6(12):2314-9. doi: 10.1038/ismej.2012.58. Epub 2012 Jun 7.
7
The impact of quorum sensing on the virulence of Aeromonas hydrophila and Aeromonas salmonicida towards burbot (Lota lota L.) larvae.群体感应对嗜水气单胞菌和杀鲑气单胞菌对江鳕(Lota lota L.)幼体毒力的影响。
Vet Microbiol. 2012 Sep 14;159(1-2):77-82. doi: 10.1016/j.vetmic.2012.03.014. Epub 2012 Mar 14.
8
LitR of Vibrio salmonicida is a salinity-sensitive quorum-sensing regulator of phenotypes involved in host interactions and virulence.发光弧菌的 LitR 是一种对盐度敏感的群体感应调节因子,调节与宿主相互作用和毒力相关表型。
Infect Immun. 2012 May;80(5):1681-9. doi: 10.1128/IAI.06038-11. Epub 2012 Feb 27.
9
Orally administered thermostable N-acyl homoserine lactonase from Bacillus sp. strain AI96 attenuates Aeromonas hydrophila infection in zebrafish.来自芽孢杆菌 AI96 的口服热稳定 N-酰基高丝氨酸内酯酶可减轻斑马鱼的嗜水气单胞菌感染。
Appl Environ Microbiol. 2012 Mar;78(6):1899-908. doi: 10.1128/AEM.06139-11. Epub 2012 Jan 13.
10
Quorum quenching quandary: resistance to antivirulence compounds.群体感应淬灭困境:抗抗病毒化合物的抗性。
ISME J. 2012 Mar;6(3):493-501. doi: 10.1038/ismej.2011.122. Epub 2011 Sep 15.