Guo Ting, Gu Chao, Feng Chenchen, Ding Qiang, Xu Congjian, Li Bin
Department of Gynaecology, Obstetrics and Gynaecology Hospital, Fudan University, China.
Wideochir Inne Tech Maloinwazyjne. 2013 Sep;8(3):187-91. doi: 10.5114/wiitm.2011.33614. Epub 2013 Mar 5.
To investigate whether intrinsic ureteral endometriosis could be managed by laser endoureterotomy.
We studied retrospectively 6 patients with intrinsic ureteral endometriosis who underwent laser endoureterotomy and reviewed their clinical data. Pathological sections of them have also been studied by immunohistochemistry for expressional levels of oestrogen (ER) and progesterone (PR) receptors. Ten sections of normal endometrium were included as a control.
Five patients had recurrence of ureteral stricture within 6 months postoperatively despite hormonal therapy for 3 to 6 months. One patient had recurrence 8 months after endoureterotomy. Two patients had secondary surgery for ureteroureterostomy and pathology confirmed recurrence of endometriosis. Immunohistochemistry revealed decreased ER and PR expression compared to the control.
Endoureterotomy with hormonal therapy may not be suitable for ureteral endometriosis due to inadequate cutting and expressional change of ER and PR.
探讨输尿管内异症能否通过激光输尿管内切开术进行治疗。
我们回顾性研究了6例行激光输尿管内切开术的输尿管内异症患者,并复习了他们的临床资料。还通过免疫组织化学研究了他们的病理切片中雌激素(ER)和孕激素(PR)受体的表达水平。纳入10例正常子宫内膜切片作为对照。
尽管进行了3至6个月的激素治疗,但5例患者在术后6个月内出现输尿管狭窄复发。1例患者在输尿管内切开术后8个月复发。2例患者接受了输尿管输尿管吻合术的二次手术,病理证实为子宫内膜异位症复发。免疫组织化学显示与对照组相比,ER和PR表达降低。
由于切割不充分以及ER和PR的表达变化,输尿管内切开术联合激素治疗可能不适用于输尿管内异症。