美西多宁和富马酸3-羟基吡啶用于慢性心肌损伤的实验依据。
Experimental substantiation for the use of mexidol and 3-hydroxypyridine fumarate in chronic myocardial injury.
作者信息
Zamotaeva M N, Chairkin I N, Inchina V I, Drozdov I A
机构信息
Department of Pharmacology, Department of Normal Anatomy, N. P. Ogarev Mordovia State University, Saransk, Russia.
出版信息
Bull Exp Biol Med. 2013 Jun;155(2):212-3. doi: 10.1007/s10517-013-2115-3.
PMID:24130992
Abstract
We studied the cardioprotective properties of mexidol and 3-hydroxypyridine fumarate in rat model of chronic myocardial injury. We found that 3-hydroxypyridine fumarate (25 mg/kg) produced more pronounced antioxidant and cardioprotective effects than mexidol (25 mg/kg).
摘要
我们在慢性心肌损伤大鼠模型中研究了美西多芬和富马酸3-羟基吡啶的心脏保护特性。我们发现，富马酸3-羟基吡啶（25毫克/千克）比美西多芬（25毫克/千克）产生更显著的抗氧化和心脏保护作用。
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