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冠状动脉搭桥手术患者左前降支动脉内膜切除术的中期结果及血管造影随访

Mid-term outcome and angiographic follow-up of endarterectomy of the left anterior descending artery in patients undergoing coronary artery bypass surgery.

作者信息

Binsalamah Ziyad M, Al-Sarraf Nael, Chaturvedi Rakesh K, Alam Ahsan, Thalib Lukman, Belley Genevieve, Shum-Tim Dominique

机构信息

Department of Surgery, Division of Cardiac Surgery, Royal Victoria Hospital, Montreal, Quebec, Canada.

出版信息

J Card Surg. 2014 Jan;29(1):1-7. doi: 10.1111/jocs.12230. Epub 2013 Oct 17.

Abstract

BACKGROUND AND AIM

With the advancement of percutaneous coronary interventions (PCIs), more patients with diffuse coronary artery disease are referred for coronary artery bypass graft (CABG) surgery. The use of coronary endarterectomy may be useful in such cases. We reviewed our experience with left anterior descending artery endarterectomy as an adjunct to conventional CABG.

METHODS

Between June 2005 and 2011, 58 consecutive patients underwent left anterior descending artery endarterectomy as an adjunct to CABG. These were matched to 58 cases based on age, gender, and Parsonnet score. All data were collected prospectively in a departmental database. Postoperative complications and in-hospital mortality were analyzed. Survival curves were produced.

RESULTS

There was one death in the endarterectomy group (1.7%) from liver failure. There was no significant difference in postoperative complications (especially perioperative myocardial infarction) between the two groups with similar hospital mortality. Computed tomography (CT) angiography was performed in 24 patients with endarterectomy (41%), which showed 100% patency of the left internal mammary artery graft to the left anterior descending artery. Survival and freedom from intervention at a mean follow-up of 4.2 years were similar.

CONCLUSIONS

In patients with diffuse disease, the use of endarterectomy is a safe technique with no increase in short-term morbidity or mortality. Mid-term results are similar to nonendarterectomized patients. This technique is useful in patients with diffuse coronary artery disease.

摘要

背景与目的

随着经皮冠状动脉介入治疗(PCI)技术的进步,越来越多弥漫性冠状动脉疾病患者被转诊接受冠状动脉旁路移植术(CABG)。在这类病例中,冠状动脉内膜切除术可能会有所帮助。我们回顾了我们将左前降支内膜切除术作为传统CABG辅助手段的经验。

方法

2005年6月至2011年期间,58例连续患者接受了左前降支内膜切除术作为CABG的辅助手段。根据年龄、性别和Parsonnet评分将这些患者与58例对照病例进行匹配。所有数据均前瞻性收集于科室数据库中。分析术后并发症和住院死亡率,并绘制生存曲线。

结果

内膜切除术组有1例(1.7%)因肝功能衰竭死亡。两组术后并发症(尤其是围手术期心肌梗死)无显著差异,住院死亡率相似。24例接受内膜切除术的患者(41%)进行了计算机断层扫描(CT)血管造影,结果显示左乳内动脉至左前降支的移植血管通畅率为100%。平均随访4.2年时的生存率和无需干预的情况相似。

结论

对于弥漫性疾病患者,内膜切除术是一种安全的技术,不会增加短期发病率或死亡率。中期结果与未接受内膜切除术的患者相似。该技术对弥漫性冠状动脉疾病患者有用。

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