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与圆顶状黄斑相关的视网膜下液的治疗。

Treatment of subretinal fluid associated with dome-shaped macula.

作者信息

Chinskey Nicholas D, Johnson Mark W

出版信息

Ophthalmic Surg Lasers Imaging Retina. 2013 Nov 1;44(6):593-5. doi: 10.3928/23258160-20131010-01. Epub 2013 Oct 18.

Abstract

Dome-shaped macula is a recently described disorder seen in eyes with myopic posterior staphyloma. Vision loss may accompany sub-macular fluid accumulation, for which no effective treatment has been reported. The authors report the successful treatment of two female patients, aged 34 and 59 years, with chronic exudative macular detachment associated with dome-shaped macula. Symptoms of subretinal fluid had been present for at least 2 years in each case, and the fluid was refractory to multiple intravitreal bevacizumab injections in one eye. After a single session of half-fluence verteporfin photodynamic therapy, the submacular fluid resolved completely in each eye. In one eye, recurrent submacular fluid 2 years later responded partially to repeat photodynamic therapy and completely to focal laser photocoagulation. [Ophthalmic Surg Lasers Imaging Retina. 2013;44:593-595.].

摘要

穹窿状黄斑是一种最近才被描述的疾病,见于患有近视性后巩膜葡萄肿的眼睛。视力丧失可能伴随黄斑下积液,目前尚无有效治疗方法的报道。作者报告了两名分别为34岁和59岁的女性患者,她们患有与穹窿状黄斑相关的慢性渗出性黄斑脱离,治疗取得成功。每例患者的视网膜下液症状至少已持续2年,其中一只眼睛的积液对多次玻璃体内注射贝伐单抗均无反应。在单次半剂量维替泊芬光动力治疗后,每只眼睛的黄斑下积液均完全消退。其中一只眼睛在2年后出现复发性黄斑下积液,再次光动力治疗部分有效,局部激光光凝治疗后完全消退。[眼科手术、激光与视网膜成像杂志。2013年;44:593 - 595。]

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