Department of Neurology, Oregon Health and Science University, Portland, Oregon, USA.
Mov Disord. 2013 Sep 15;28(11):1560-5. doi: 10.1002/mds.25673.
The term higher-level gait disorders (HLGD) defines a category of balance and gait disorders that are not explained by deficits in strength, tone, sensation, or coordination. HLGD are characterized by various combinations of disequilibrium and impaired locomotion. A plethora of new imaging techniques are beginning to determine the neural circuits that are the basis of these disorders. Although a variety of neurodegenerative and other pathologies can produce HLGD, the most common cause appears to be microvascular disease that causes white-matter lesions and thereby disrupts balance/locomotor circuits.
高级步态障碍（HLGD）一词定义了一类平衡和步态障碍，这些障碍不能用力量、张力、感觉或协调的缺陷来解释。HLGD 的特征是各种平衡和运动障碍的组合。大量新的成像技术开始确定这些障碍的神经回路基础。虽然各种神经退行性和其他病理学都可能导致 HLGD，但最常见的原因似乎是微血管疾病，它会导致白质病变，从而破坏平衡/运动回路。
