Liu Haiyan, Gu Weirong, Li Xiaotian
Obstetrics and Gynecology Hospital, Fudan University, 419 Fangxie Road, Shanghai, 200011, China.
J Clin Ultrasound. 2014 Feb;42(2):74-80. doi: 10.1002/jcu.22101. Epub 2013 Oct 17.
To evaluate the natural history and outcome of pregnancies in patients with placental chorioangioma.
A total of 16 placentas with a histologic diagnosis of chorioangioma were identified, and the natural history and outcome of pregnancy were evaluated. This study was approved by the Institutional Ethics Committees of our unit, and written informed consent was obtained from all study participants.
Thirteen of the 16 cases were associated with a wide variety of fetal complications. Two-thirds of the cases developed complications that either required elective delivery because of fetal distress (n = 4), fetal heart failure (n = 1), oligohydramnion (n = 1), and premature labor of dichorionic twins (n = 1) or resulted in intrauterine fetal death and termination of pregnancy (n = 2).
Placental chorioangioma was associated with the development of polyhydramnios, fetal growth restriction, and fetal distress in a significant number of cases. The size, vascularity, and location of the chorioangioma may be three independent factors of maternal and fetal complications. Any of these three factors can influence the outcome of pregnancy. Close antenatal examination should be routinely practiced to allow the timely diagnosis of early fetal heart failure.
评估胎盘绒毛膜血管瘤患者妊娠的自然病史及结局。
共识别出16例经组织学诊断为绒毛膜血管瘤的胎盘，并对妊娠的自然病史及结局进行评估。本研究经本单位机构伦理委员会批准，所有研究参与者均签署了书面知情同意书。
16例中有13例伴有多种胎儿并发症。三分之二的病例出现了并发症，其中因胎儿窘迫（n = 4）、胎儿心力衰竭（n = 1）、羊水过少（n =
1）及双绒毛膜双胎早产（n = 1）而需要择期分娩，或导致胎儿宫内死亡及终止妊娠（n = 2）。
在相当多的病例中，胎盘绒毛膜血管瘤与羊水过多、胎儿生长受限及胎儿窘迫的发生有关。绒毛膜血管瘤的大小、血管分布及位置可能是影响母胎并发症的三个独立因素。这三个因素中的任何一个都可能影响妊娠结局。应常规进行密切的产前检查，以便及时诊断早期胎儿心力衰竭。
