Teng Yao-Shu, Lin Zhi-Hong, Li Yong, Cao Xiao-Lin, Lin Feng-Chun, Xiang Jing-Jing
Department of Otorhinolaryngology, Hangzhou First People's Hospital Hangzhou, 310006, P.R. China.
Int J Clin Exp Pathol. 2013 Sep 15;6(10):2257-62. eCollection 2013.
Synovial sarcoma is an uncommon, aggressive malignant tumor of the soft tissues primarily involving the extremities of young adults. Head and neck synovial sarcoma is rare, and its diagnosis and therapy are still challenging.We report a case of a young patient with synovial sarcoma, clinically masquerading as cystic mass of the neck and malignant second branchial cleft cyst. The pathological diagnosis of the sarcoma was confirmed by a multimodality diagnostic protocol, including histological, immunohistochemical and molecular genetic analysis. The patient underwent complete surgical excision followed by postoperative radiotherapy and recovered well.
滑膜肉瘤是一种罕见的、侵袭性的软组织恶性肿瘤，主要累及年轻成年人的四肢。头颈部滑膜肉瘤罕见，其诊断和治疗仍然具有挑战性。我们报告一例年轻的滑膜肉瘤患者，临床上伪装成颈部囊性肿块和恶性第二鳃裂囊肿。通过包括组织学、免疫组织化学和分子遗传学分析在内的多模态诊断方案确诊了肉瘤的病理诊断。患者接受了完整的手术切除，随后进行了术后放疗，恢复良好。
