Neyton J, Trautmann A
Nature. 1985;317(6035):331-5. doi: 10.1038/317331a0.
We have used a double whole-cell patch-clamp system to make the first quantitative recordings of the single-channel current from an intercellular junction, presumably a gap junction. The junctional channel has various conductance states and discriminates poorly between cations and anions. It seems to change slowly from one conductance state to another.
我们使用双全细胞膜片钳系统,首次对来自细胞间连接(可能是缝隙连接)的单通道电流进行了定量记录。连接通道具有多种电导状态,对阳离子和阴离子的区分能力较差。它似乎会缓慢地从一种电导状态转变为另一种电导状态。