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腰椎融合术及封顶手术的有限元分析

[Finite element analysis of lumbar fusion and Topping-off surgery].

作者信息

Liu Hai-Ying, Wang Jie-Fu, Zhu Zhen-Qi

机构信息

Department of Spinal Surgery, Peking University People's Hospital, Beijing 100044, China.

出版信息

Beijing Da Xue Xue Bao Yi Xue Ban. 2013 Oct 18;45(5):723-7.

Abstract

OBJECTIVE

To evaluate the effect of Topping-off surgery on the adjacent segment of PLIF.

METHODS

A finite element model of the human lumbar spine (L1-L5) was developed. The intact spinal model was validated by comparing it with previously reported models. Then, 2 models were analyzed and compared: (1) posterior lumbar interbody fusion (PLIF) at L4/5; (2) posterior lumbar interbody fusion at L4/5 and implantation of the interspinous spacer (ISP) at L3/4 (Topping-off). Then 500 N compressive loading plus 10 Nm moments simulating flexion, extension, lateral bending and axial rotation were imposed on both the L1 superior endplates. The ranges of motion, intradiscal pressures, facet stresses in L3/4, the stresses on spinous processes in L3 and L4 were investigated. All the measured data were analyzed by SPSS 21.0.

RESULTS

The effect of the Topping-off on the adjacent segment appeared mainly in flexion-extension: the ranges of motion, intradiscal pressures (annulus and nucleus pulposus), both facet stresses were lower than that of the PLIF model, and the stresses on spinous processes in L3 and L4 were larger. Besides, the facet stresses on the left side in the left lateral bending were also lower than those of the PLIF model.

CONCLUSION

Topping-off model is able to restrict the range of motion of the lumbar adjacent segment, decrease the intradiscal pressure and facet stresses, and has a potential effect of preventing adjacent segmental degeneration.

摘要

目的

评估椎体间撑开植骨术对腰椎后路椎间融合术(PLIF)相邻节段的影响。

方法

建立人体腰椎(L1-L5)的有限元模型。通过与先前报道的模型进行比较,对完整的脊柱模型进行验证。然后,分析并比较2个模型:(1)L4/5节段的腰椎后路椎间融合术(PLIF);(2)L4/5节段的腰椎后路椎间融合术及L3/4节段棘突间植入物(ISP)(椎体间撑开植骨术)。然后,在L1上终板施加500 N的压缩载荷加10 Nm的力矩,模拟前屈、后伸、侧弯和轴向旋转。研究L3/4节段的活动范围、椎间盘内压力、小关节应力,以及L3和L4棘突上的应力。所有测量数据均采用SPSS 21.0进行分析。

结果

椎体间撑开植骨术对相邻节段的影响主要出现在前屈-后伸时:活动范围、椎间盘内压力(纤维环和髓核)、双侧小关节应力均低于PLIF模型,L3和L4棘突上的应力更大。此外,左侧侧弯时左侧的小关节应力也低于PLIF模型。

结论

椎体间撑开植骨术模型能够限制腰椎相邻节段的活动范围,降低椎间盘内压力和小关节应力,具有预防相邻节段退变的潜在作用。

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