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日托中心的水痘暴发:在此环境中预防水痘暴发的挑战与机遇

Varicella outbreak in a daycare: challenges and opportunities for preventing varicella outbreaks in this setting.

作者信息

Daskalaki Irini, Thermitus Rodrerica, Perella Dana, Viner Kendra, Spells Niya, Mohanty Salini, Lopez Adriana, Johnson Caroline

机构信息

From the *Division of Disease Control, Philadelphia Department of Public Health; †Department of Pediatrics, Drexel University College of Medicine; ‡Department of Pediatrics, St Christopher's Hospital for Children, Philadelphia, PA; and §Centers for Disease Control and Prevention, Atlanta, GA.

出版信息

Pediatr Infect Dis J. 2014 Apr;33(4):420-2. doi: 10.1097/INF.0000000000000127.

Abstract

As a result of single-dose varicella vaccination, daycare outbreaks have become rare. We investigated a daycare outbreak resulting from a misdiagnosed varicella case in an unvaccinated attendee. Of 25 attendees aged 12-32 months without evidence of immunity, 7 (28%) were unvaccinated due to religious/philosophical opposition or recent 1st birthday. Single-dose vaccination reduced disease by 92% compared with no vaccination.

摘要

由于接种了单剂量水痘疫苗,日托中心的水痘疫情已变得罕见。我们调查了一起因一名未接种疫苗的日托中心参与者水痘病例误诊而导致的疫情。在25名年龄在12至32个月且无免疫证据的参与者中,有7人(28%)因宗教/哲学上的反对或刚满1周岁而未接种疫苗。与未接种疫苗相比,单剂量接种使疾病发生率降低了92%。

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