Jiang Yangping, Lan Huanrong, Ye Qian, Jin Ketao, Zhu Min, Hu Xiaoyan, Teng Lisong, Cao Feilin, Lin Xianfang
Department of Surgical Oncology, Dongyang Hospital, Wenzhou Medical University, Dongyang, Zhejiang 322100, P.R. China.
Exp Ther Med. 2013 Sep;6(3):759-764. doi: 10.3892/etm.2013.1191. Epub 2013 Jul 1.
Ultrasound-guided vacuum-assisted breast biopsy (VABB) is regarded as a feasible, effective, minimally invasive and safe method for the removal of benign breast lesions, without the occurrence of serious complications. The aim of this study was to evaluate the feasibility, efficacy and safety of ultrasound-guided VABB using the Mammotome biopsy system in the treatment of breast lesions. The clinical outcomes of 3,681 patients with breast lesions were evaluated following excisions by ultrasound-guided VABB in two high-volume teaching hospitals. From January 2008 to December 2012, a total of 4,867 ultrasound-guided VABB procedures were performed in the 3,681 patients, who had a mean age of 37.8 years (range, 16-73 years). The parameters examined in this analysis included lesion size, lesion location in the inner breast, Breast Imaging Reporting and Data System (BI-RADS) ultrasound category and histopathological diagnosis. Ultrasonography follow-up was performed at 3-6 month intervals in order to assess recurrence. The size of the investigated lesions ranged between 6 and 62 mm and a histopathological diagnosis was made in 100% of cases. The results indicated that the majority of specimens (98.89%) were benign. On average, the ultrasound-guided VABB was performed in 10.3 min (range, 7.5-43 min) and the mean number of cores removed in the procedure was 8.1 (range, 3-32). A complete excision was achieved in the majority of cases (99.7%). The presence of a hematoma was the most common complication following the biopsy, and was observed in 27.5% of patients. The mean follow-up period was 25.5 months (range, 1-60 months), during which the rate of recurrence was 4.4%. The results indicated that ultrasound-guided VABB using the Mammotome biopsy system is an effective and safe procedure that is able to rapidly remove the majority of benign breast lesions using a small incision and without the occurrence of scarring or complications.
超声引导下真空辅助乳腺活检（VABB）被认为是一种可行、有效、微创且安全的切除乳腺良性病变的方法，不会发生严重并发症。本研究的目的是评估使用麦默通活检系统进行超声引导下VABB治疗乳腺病变的可行性、有效性和安全性。在两家大型教学医院对3681例乳腺病变患者进行超声引导下VABB切除术后，评估其临床结局。2008年1月至2012年12月，3681例患者共接受了4867例超声引导下VABB手术，患者平均年龄为37.8岁（范围16 - 73岁）。本分析中检查的参数包括病变大小、乳腺内侧病变位置、乳腺影像报告和数据系统（BI-RADS）超声分类以及组织病理学诊断。每隔3 - 6个月进行超声随访以评估复发情况。所研究病变的大小在6至62毫米之间，100%的病例进行了组织病理学诊断。结果表明，大多数标本（98.89%）为良性。平均而言，超声引导下VABB手术时间为10.3分钟（范围7.5 - 43分钟），手术中平均取出的芯样数量为8.1个（范围3 - 32个）。大多数病例（99.7%）实现了完整切除。活检后最常见的并发症是血肿，27.5%的患者出现该并发症。平均随访期为25.5个月（范围1 - 60个月），在此期间复发率为4.4%。结果表明，使用麦默通活检系统的超声引导下VABB是一种有效且安全的手术方法，能够通过小切口快速切除大多数乳腺良性病变，且不会出现瘢痕或并发症。
