Department of Electronic Engineering, Fudan University, 200433 Shanghai, China.
Department of Electronic Engineering, Fudan University, 200433 Shanghai, China.
Ultrasonics. 2014 Jul;54(5):1210-8. doi: 10.1016/j.ultras.2013.09.015. Epub 2013 Sep 27.
Guided modes propagation in intact, fractured and healing long bone has drawn significant research interests. However, mode quantifications for the direct comparison are still necessary to address. The aim of the study is to analyze the mode interaction with a notch-fracture in the long bone and find quantitative ultrasound parameters sensitive to depth and width variation of the fracture. We analyzed the impacts of the partially and completely diaphyseal osteotomy on fundamental guided modes propagation using the two-dimension finite-difference time-domain (2D-FDTD) simulations. The long bones were built as three layer models by a cortical plate embedded between overlying soft tissue and inner-coated marrow. Narrowband low-frequency sinusoids (100 kHz) were employed to only excite two fundamental guided modes. The mode amplitude variations were investigated as functions of the gap-breakage width and depth. It is found that the transverse fractures have strong influences on the anti-symmetric mode A0 transmission and reflection, whereas amplitudes of the symmetric mode S0 are not sensitive to the fracture degree. The quantitative results consistently indicate that reflection energy and transmission coefficients of the S0 and A0 modes can be used to quantify the mode interaction in the fractured long bone and further to evaluate long bone fracture status. Future study is needed to investigate the physical experiments on realistic fractured long bone and to insure that the proposed ultrasound parameters can be used to quantitatively evaluate the long bone fracture in clinical application.
在完整、断裂和愈合的长骨中引导模的传播引起了广泛的研究兴趣。然而,为了进行直接比较,仍然需要对模式进行量化。本研究的目的是分析带有切痕的长骨中的模式相互作用,并找到对骨折深度和宽度变化敏感的定量超声参数。我们使用二维有限差分时域(2D-FDTD)模拟分析了部分和完全骨干截骨对基本引导模传播的影响。长骨通过嵌入在上覆软组织和内部涂层骨髓之间的皮质板构建为三层模型。窄带低频正弦波(100 kHz)仅用于激发两个基本引导模。研究了模式幅度变化作为间隙断裂宽度和深度的函数。结果发现,横向骨折对反对称模 A0 的透射和反射有很强的影响,而对称模 S0 的幅度对骨折程度不敏感。定量结果一致表明,S0 和 A0 模式的反射能量和透射系数可用于量化骨折长骨中的模式相互作用,并进一步评估长骨骨折状态。未来需要对现实骨折长骨进行物理实验研究,并确保所提出的超声参数可用于临床应用中定量评估长骨骨折。