Dodd S P, Miles A W, Gheduzzi S, Humphrey V F, Cunningham J L
Department of Mechanical Engineering, University of Bath, Bath, Avon, UK.
Comput Methods Biomech Biomed Engin. 2007 Oct;10(5):371-5. doi: 10.1080/10255840701502387.
The effect on the signal amplitude of ultrasonic waves propagating along cortical bone plates was modelled using a 2D Finite Difference code. Different healing stages, represented by modified fracture geometries were introduced to the plate model. A simple transverse and oblique fracture filled with water was introduced to simulate the inflammatory stage. Subsequently, a symmetric external callus surrounding a transverse fracture was modelled to represent an advanced stage of healing. In comparison to the baseline (intact plate) data, a large net loss in signal amplitude was produced for the simple transverse and oblique cases. Changing the geometry to an external callus with different mechanical properties caused the net loss in signal amplitude to reduce significantly. This relative change in signal amplitude as the geometry and mechanical properties of the fracture site change could potentially be used to monitor the healing process.
使用二维有限差分代码对沿皮质骨板传播的超声波信号幅度的影响进行了建模。通过修改骨折几何形状来表示不同的愈合阶段，并将其引入到板模型中。引入一个简单的充满水的横向和斜向骨折来模拟炎症阶段。随后，对围绕横向骨折的对称外部骨痂进行建模，以代表愈合的晚期阶段。与基线（完整板）数据相比，简单的横向和斜向情况导致信号幅度出现大幅净损失。将几何形状改变为具有不同力学性能的外部骨痂，使得信号幅度的净损失显著降低。随着骨折部位的几何形状和力学性能变化而产生的这种信号幅度相对变化，有可能用于监测愈合过程。
