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网格蛋白介导入胞作用的新兴和制动消息。

Budding and braking news about clathrin-mediated endocytosis.

机构信息

Department of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706, USA.

出版信息

Curr Opin Plant Biol. 2013 Dec;16(6):718-25. doi: 10.1016/j.pbi.2013.09.005. Epub 2013 Oct 15.

DOI:10.1016/j.pbi.2013.09.005
PMID:24139529
Abstract

Clathrin-mediated endocytosis (CME) is the predominate mechanism of endocytosis in eukaryotes, but an understanding of this mechanism in plants has lagged behind yeast and mammalian systems. The generation of Arabidopsis mutant libraries, and the development of the molecular tools and equipment necessary to characterize these plant lines has led to an astonishing number of new insights into the mechanisms of membrane trafficking in plants. Over the past few years progress has been made on identifying, and in some instances confirming, the core components of CME in plants. This review focuses on the recent progress made in the understanding of the mechanism and regulation of CME in plants.

摘要

网格蛋白介导的内吞作用(CME)是真核生物中主要的内吞作用机制,但人们对植物中这一机制的理解落后于酵母和哺乳动物系统。拟南芥突变体文库的产生,以及鉴定这些植物品系所需的分子工具和设备的发展,使得人们对植物中膜运输的机制有了惊人数量的新见解。在过去的几年中,人们在鉴定和在某些情况下证实植物中 CME 的核心成分方面取得了进展。本文综述了近年来人们在理解植物中 CME 的机制和调控方面取得的进展。

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