基于 DNA zyme 诱导的催化反应的用于铅检测的 MRI 生物传感器。
MRI biosensor for lead detection based on the DNAzyme-induced catalytic reaction.
机构信息
State Key Lab of Food Science and Technology, School of Food Science and Technology, Jiangnan University , Wuxi, JiangSu 214122, People's Republic of China.
出版信息
J Phys Chem B. 2013 Nov 21;117(46):14367-71. doi: 10.1021/jp4087656. Epub 2013 Nov 7.
PMID:24143944
Abstract
A MRI biosensor for sensitive and specific detection of lead ions (Pb(2+)) was developed based on DNAzyme-induced cleavage of magnetic nanoparticles (MNPs). A low limit of detection (LOD) of 0.05 ng mL(-1) was obtained. This biosensor has the potential to serve as a general platform for the detection of heavy metal ions.
摘要
一种基于 DNA zyme 诱导的磁性纳米粒子（MNPs）裂解的用于灵敏和特异性检测铅离子（Pb(2+)）的 MRI 生物传感器被开发出来。该生物传感器的检测限（LOD）低至 0.05ng mL(-1)。该生物传感器有望成为一种通用的重金属离子检测平台。
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