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Structural and biological studies on bacterial nitric oxide synthase inhibitors.
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2
Inhibitor Bound Crystal Structures of Bacterial Nitric Oxide Synthase.
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Identification of redox partners and development of a novel chimeric bacterial nitric oxide synthase for structure activity analyses.
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Endogenous nitric oxide protects bacteria against a wide spectrum of antibiotics.
Science. 2009 Sep 11;325(5946):1380-4. doi: 10.1126/science.1175439.
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Structure-based design of bacterial nitric oxide synthase inhibitors.
J Med Chem. 2015 Jan 22;58(2):994-1004. doi: 10.1021/jm501723p. Epub 2015 Jan 6.
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Targeting Bacterial Nitric Oxide Synthase with Aminoquinoline-Based Inhibitors.
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Structural basis for isoform-selective inhibition in nitric oxide synthase.
Acc Chem Res. 2013 Feb 19;46(2):390-8. doi: 10.1021/ar300175n. Epub 2012 Oct 2.
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Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat Struct Mol Biol. 2004 Jan;11(1):54-9. doi: 10.1038/nsmb704. Epub 2003 Dec 29.

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A Tetrahydrobiopterin-Displacing Potent Neuronal Nitric Oxide Synthase Inhibitor with an Unprecedented Binding Mode.
ACS Med Chem Lett. 2025 Mar 21;16(4):651-659. doi: 10.1021/acsmedchemlett.5c00062. eCollection 2025 Apr 10.
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Sulfinamide Formation from the Reaction of Bacillithiol and Nitroxyl.
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Nitric Oxide, Nitric Oxide Formers and Their Physiological Impacts in Bacteria.
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The Response of and Contributes to Virulence and Metabolism.
J Bacteriol. 2019 Apr 9;201(9). doi: 10.1128/JB.00107-19. Print 2019 May 1.
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Antibacterial Efficacy of Silver Nanoparticles on Endometritis Caused by and in Dairy Cattle.
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"On demand" redox buffering by HS contributes to antibiotic resistance revealed by a bacteria-specific HS donor.
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Oxidative Phosphorylation as a Target Space for Tuberculosis: Success, Caution, and Future Directions.
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Structural basis for isoform-selective inhibition in nitric oxide synthase.
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