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术前尿比重与髋部骨折手术后并发症的发生率:一项前瞻性、观察性研究。

Preoperative urine-specific gravity and the incidence of complications after hip fracture surgery: A prospective, observational study.

机构信息

From the Department of Anaesthesiology, Vrinnevi Hospital, Norrköping (SIY, OE, KB, HK), and the Department of Anaesthesiology, Linköping University, Linköping, Sweden (JHZ, RGH).

出版信息

Eur J Anaesthesiol. 2014 Feb;31(2):85-90. doi: 10.1097/01.EJA.0000435057.72303.0e.

Abstract

BACKGROUND

Mild to moderately severe dehydration is common in the elderly, but its relationship to surgical outcome is unclear.

OBJECTIVES

To study the incidence of dehydration prior to hip fracture surgery and its relationship to postoperative complications.

DESIGN

Prospective observational study.

SETTING

Operation department and orthopaedic ward at a regional hospital.

PATIENTS

Forty-five patients [median (interquartile range) age 78 (75 to 86) years] undergoing acute hip fracture surgery.

INTERVENTIONS

A urine sample was taken on admission to the operating theatre. Complications were assessed 2 days postoperatively using a check-list.

MAIN OUTCOME MEASURES

Dehydration was considered to be present if the urinary specific gravity was 1.020 or higher, indicating renal water conservation. The number and type of postoperative complications were recorded.

RESULTS

Dehydration was present in one third of the patients. Sixty percent of these patients had at least one postoperative complication, whereas the corresponding proportion was 30% in the euhydrated patients (P < 0.01). Only one patient (3%) had more than one complication in the euhydrated group compared with six patients (40%) in the dehydrated group (P < 0.01). Euhydrated patients had a mean of 0.3 postoperative complications per surgery, whereas dehydrated patients scored 1.1 complications (P < 0.015). The higher incidence included confusion, arterial desaturation and cardiovascular events.

CONCLUSION

Dehydration before surgery nearly quadrupled the number of postoperative complications after hip fracture repair.

TRIAL REGISTRATION

clinicaltrials.gov Identifier: NCT 01294930.

摘要

背景

轻度至中度脱水在老年人中很常见,但它与手术结果的关系尚不清楚。

目的

研究髋部骨折手术前脱水的发生率及其与术后并发症的关系。

设计

前瞻性观察研究。

地点

区域医院的手术室和骨科病房。

患者

45 例[中位数(四分位数间距)年龄 78(75 至 86)岁]接受急性髋部骨折手术的患者。

干预措施

在进入手术室时采集尿液样本。术后 2 天使用清单评估并发症。

主要观察指标

如果尿比重为 1.020 或更高,表明肾脏保水,则认为存在脱水。记录术后并发症的数量和类型。

结果

三分之一的患者存在脱水。这些患者中有 60%至少有一种术后并发症,而在未脱水患者中这一比例为 30%(P < 0.01)。在未脱水组中只有 1 名患者(3%)有 1 种以上并发症,而在脱水组中则有 6 名患者(40%)(P < 0.01)。未脱水患者每例手术的术后并发症平均为 0.3 例,而脱水患者为 1.1 例(P < 0.015)。较高的发生率包括意识混乱、动脉血氧饱和度降低和心血管事件。

结论

髋部骨折修复术后,术前脱水使术后并发症的发生率几乎增加了 4 倍。

临床试验注册

clinicaltrials.gov 标识符:NCT 01294930。

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