Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, PR China.
Talanta. 2013 Nov 15;116:223-30. doi: 10.1016/j.talanta.2013.04.008. Epub 2013 Apr 30.
Here, we report on a novel nonenzymatic amperometric glucose sensor based on CuO nanoneedle/graphene/carbon nanofiber modified electrode. The results of the scanning electron microscopy indicate that electronic network was formed through their direct binding with the graphene/carbon nanofiber, which leads to larger active surface areas and faster electron transfer for the glucose sensor. High electrocatalytic activity toward the oxidation of glucose was observed with a rapid response (<2 s), a low detection limit (0.1 µM), a wide and useful linear range (1-5.3 mM) as well as good stability and repeatability. Moreover, the common interfering species, such as ascorbic acid, uric acid, dopamine and so forth did not cause obvious interference. The sensor can also be used for quantification of glucose concentration in real saliva samples. Therefore, this work has demonstrated a simple and effective sensing platform for nonenzymatic detection of glucose.
在这里，我们报告了一种基于氧化铜纳米针/石墨烯/碳纳米纤维修饰电极的新型非酶安培葡萄糖传感器。扫描电子显微镜的结果表明，通过它们与石墨烯/碳纳米纤维的直接结合形成了电子网络，这导致葡萄糖传感器具有更大的活性表面积和更快的电子转移。对葡萄糖的氧化具有高电催化活性，具有快速响应(<2 s)、低检测限(0.1 μM)、宽且有用的线性范围(1-5.3 mM)以及良好的稳定性和可重复性。此外，常见的干扰物质，如抗坏血酸、尿酸、多巴胺等，不会引起明显的干扰。该传感器还可用于定量分析实际唾液样本中的葡萄糖浓度。因此，这项工作展示了一种用于非酶检测葡萄糖的简单有效的传感平台。
