Hudspeth A J
Science. 1985 Nov 15;230(4727):745-52. doi: 10.1126/science.2414845.
A crucial event in the hearing process is the transduction of mechanical stimuli into electrical signals by hair cells, the sensory receptors of the internal ear. Stimulation results in the rapid opening of ionic channels in the mechanically sensitive organelles of these cells, their hair bundles. These transduction channels, which are nonselectively permeable, are directly excited by hair-bundle displacement. Hair cells are selectively responsive to particular frequencies of stimulation, both due to the mechanical properties of their hair bundles and because of an ensemble of ionic channels that constitute an electrical resonator.
听觉过程中的一个关键事件是毛细胞（内耳的感觉感受器）将机械刺激转化为电信号。刺激会导致这些细胞机械敏感细胞器（即它们的毛束）中的离子通道迅速打开。这些转导通道具有非选择性通透性，直接由毛束位移激发。毛细胞对特定频率的刺激具有选择性反应，这既是由于其毛束的机械特性，也是因为构成电谐振器的一组离子通道。
