Kyriacou V, Mavridou Ch, Bintoudi A, Tzikos F, Kotziamani N, Tsitouridis I
Radiology Department, Papageorgiou General Hospital; Thessaloniki, Greece -
Neuroradiol J. 2010 Oct;23(5):607-12. doi: 10.1177/197140091002300510. Epub 2010 Oct 31.
Magnetic resonance imaging (MRI) in patients with congenital growth hormone deficiency (GHD) has revealed several morphological abnormalities of the hypothalamo-pituitary region which include hypoplasia of the anterior pituitary lobe, the absence or marked thinning of the pituitary stalk and ectopia of the posterior pituitary lobe (EPP). This triad of abnormalities is called pituitary stalk interruption syndrome (PSIS). Our study reports the imaging findings of 23 patients with idiopathic GHD and short stature who were examined by MRI. The majority of the patients had abnormal MR studies with findings indicating the presence of the pituitary stalk syndrome. The high correlation between the clinical profile and the MR findings in cases of pituitary dysfunction (most often GHD), defines the significant role of MRI as additional tool for the diagnosis of pituitary hormone deficiency.
先天性生长激素缺乏症（GHD）患者的磁共振成像（MRI）显示下丘脑 - 垂体区域存在多种形态学异常，包括垂体前叶发育不全、垂体柄缺如或明显变细以及垂体后叶异位（EPP）。这一异常三联征被称为垂体柄中断综合征（PSIS）。我们的研究报告了23例特发性GHD和身材矮小患者经MRI检查的影像学结果。大多数患者的MR检查结果异常，提示存在垂体柄综合征。垂体功能障碍（最常见的是GHD）病例的临床特征与MR结果之间的高度相关性，确定了MRI作为诊断垂体激素缺乏的辅助工具的重要作用。
