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高分辨率重度T2加权磁共振成像用于评估异位神经垂体患儿的垂体柄。

High-resolution heavily T2-weighted magnetic resonance imaging for evaluation of the pituitary stalk in children with ectopic neurohypophysis.

作者信息

El Sanharawi Imane, Tzarouchi Loukia, Cardoen Liesbeth, Martinerie Laetitia, Leger Juliane, Carel Jean-Claude, Elmaleh-Berges Monique, Alison Marianne

机构信息

Service de Radiologie Pédiatrique, Hôpital Robert Debré, APHP, 48 boulevard Sérurier, 75019, Paris, France.

Université Paris Diderot, Paris, France.

出版信息

Pediatr Radiol. 2017 May;47(5):599-605. doi: 10.1007/s00247-017-3784-2. Epub 2017 Mar 2.

DOI:10.1007/s00247-017-3784-2
PMID:28255689
Abstract

BACKGROUND

In anterior pituitary deficiency, patients with non visible pituitary stalk have more often multiple deficiencies and persistent deficiency than patients with visible pituitary stalk.

OBJECTIVE

To compare the diagnostic value of a high-resolution heavily T2-weighted sequence to 1.5-mm-thick unenhanced and contrast-enhanced sagittal T1-weighted sequences to assess the presence of the pituitary stalk in children with ectopic posterior pituitary gland.

MATERIALS AND METHODS

We retrospectively evaluated the MRI data of 14 children diagnosed with ectopic posterior pituitary gland between 2010 and 2014. We evaluated the presence of a pituitary stalk using a sagittal high-resolution heavily T2-weighted sequence and a 1.5-mm sagittal T1-weighted turbo spin-echo sequence before and after contrast medium administration.

RESULTS

A pituitary stalk was present on at least one of the sequences in 10 of the 14 children (71%). T2-weighted sequence depicted the pituitary stalk in all 10 children, whereas the 1.5-mm-thick T1-weighted sequence depicted 2/10 (20%) before contrast injection and 8/10 (80%) after contrast injection (P=0.007).

CONCLUSION

Compared with 1.5-mm-thick contrast-enhanced T1-weighted sequences, high-resolution heavily T2-weighted sequence demonstrates better sensitivity in detecting the pituitary stalk in children with ectopic posterior pituitary gland, suggesting that contrast injection is unnecessary to assess the presence of a pituitary stalk in this setting.

摘要

背景

在前叶垂体功能减退症中,垂体柄不可见的患者比垂体柄可见的患者更常出现多种功能减退及持续性功能减退。

目的

比较高分辨率重T2加权序列与1.5毫米厚的未增强及增强矢状位T1加权序列对评估异位垂体后叶患儿垂体柄存在情况的诊断价值。

材料与方法

我们回顾性评估了2010年至2014年间诊断为异位垂体后叶的14名儿童的MRI数据。我们使用矢状位高分辨率重T2加权序列以及造影剂注射前后的1.5毫米矢状位T1加权快速自旋回波序列评估垂体柄的存在情况。

结果

14名儿童中有10名(71%)在至少一个序列上显示有垂体柄。T2加权序列在所有10名儿童中均显示出垂体柄,而1.5毫米厚的T1加权序列在注射造影剂前显示出2/10(20%),注射造影剂后显示出8/10(80%)(P = 0.007)。

结论

与1.5毫米厚的增强T1加权序列相比,高分辨率重T2加权序列在检测异位垂体后叶患儿的垂体柄方面显示出更好的敏感性,这表明在此情况下评估垂体柄是否存在无需注射造影剂。

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