Erdogru Tibet, Avci Egemen, Akand Murat
Department of Urology, Minimally Invasive and Robotic Surgery Center, Memorial Istanbul Atasehir Hospital, Vedat Gunyol Street, Nr:30-31, Istanbul, Turkey,
Surg Endosc. 2014 Mar;28(3):925-32. doi: 10.1007/s00464-013-3248-1. Epub 2013 Oct 23.
We aimed in this study to investigate the efficacy of laparoscopic pudendal nerve decompression and transposition (LaPNDT) in the treatment of chronic pelvic pain due to pudendal neuralgia. Pudendal nerve entrapment (PNE) between the sacrospinous and sacrotuberous ligaments is the most frequent etiology. We describe the technical details, feasibility, and advantages of a laparoscopic approach in patients with PNE.
Consecutive patients (n = 27) with a diagnosis of PNE underwent LaPNDT with omental flap protection in an effort to prevent re-fibrosis around the nerve in the long term. The degree of pain and pain impact were evaluated pre- and postoperatively using the visual analog pain scale (VAS) and the Impact of Symptoms and Quality of Life.
The mean (± standard deviation [SD]) follow-up of the 27 patients was 6.8 ± 4.2 months; 16 of the 27 were followed-up for more than 6 months. The mean (SD) operation time was 199.4 ± 36.1 (155-300) min, and the mean estimated blood loss was 39.7 ml. All patients were ambulated on the first postoperative day, and the mean (SD) hospitalization time was 2.1 ± 1.0 (1-6) days. The mean VAS scores of 27, 23, 16, and 6 patients were 1.5, 1.4, 1.6, and 2.0, postoperatively, at the first, third, sixth, and twelfth months (p < 0.0001). A more than reduction in VAS score (>80 %) was achieved in 13 of the 16 patients (81.2 %) who were followed-up for more than 6 months.
LaPNDT seems a feasible surgical modality for cautiously selected patients with PNE. In addition, using an omental flap for protection of the nerve is one of the most important technical advantages of laparoscopy. As a minimally invasive surgery, the laparoscopic approach can be technically feasible, with its promising preliminary results in the treatment of PNE. With further analysis, in the future it may open new frontiers for pudendal nerve neuromodulation as a new treatment modality in some intractable functional problems of the genitourinary tract.
本研究旨在探讨腹腔镜下阴部神经减压及转位术(LaPNDT)治疗阴部神经痛所致慢性盆腔疼痛的疗效。骶棘韧带和骶结节韧带之间的阴部神经卡压(PNE)是最常见的病因。我们描述了腹腔镜手术在PNE患者中的技术细节、可行性及优势。
连续27例诊断为PNE的患者接受了LaPNDT并采用网膜瓣保护,以长期预防神经周围再纤维化。术前及术后使用视觉模拟疼痛量表(VAS)以及症状影响和生活质量量表评估疼痛程度及疼痛影响。
27例患者的平均(±标准差[SD])随访时间为6.8±4.2个月;27例中有16例随访时间超过6个月。平均(SD)手术时间为199.4±36.1(155 - 300)分钟,平均估计失血量为39.7毫升。所有患者术后第一天即可下床活动,平均(SD)住院时间为2.1±1.0(1 - 6)天。27例、23例、16例和6例患者术后、术后第1个月、第3个月、第6个月和第12个月的平均VAS评分分别为1.5、1.4、1.6和2.0(p < 0.0001)。在随访时间超过6个月的16例患者中,有13例(81.2%)VAS评分降低超过80%。
对于谨慎选择的PNE患者,LaPNDT似乎是一种可行的手术方式。此外,使用网膜瓣保护神经是腹腔镜手术最重要的技术优势之一。作为一种微创手术,腹腔镜手术在技术上可行,在治疗PNE方面取得了有前景的初步结果。随着进一步分析,未来它可能为阴部神经神经调节开辟新的领域,作为治疗一些难治性泌尿生殖道功能问题的新治疗方式。