Okolo A A, Omene J A
Ann Trop Paediatr. 1985 Sep;5(3):123-6. doi: 10.1080/02724936.1985.11748376.
The pattern of neonatal septicaemia in a large cosmopolitan African city is presented. Comparison of microorganisms isolated in the present study when compared with the results of previous reports from the same institution, show an increase in the incidence of klebsiella and pseudomonas septicaemia. In contrast, Escherichia coli infection has decreased appreciably from an incidence of 56.8% to 14.3%. Staphylococcus aureus has remained the dominant Gram-positive pathogen over the last decade while group B streptococcal (GBS) disease was rarely encountered. A significant finding was the emergence of gentamicin-resistant strains of E. coli and proteus species during the past 5 years. The overall incidence of neonatal septicaemia was 5.6/1000 livebirths and the mortality rate was 30.6%.
本文介绍了一个非洲国际化大都市的新生儿败血症模式。将本研究中分离出的微生物与同一机构先前报告的结果进行比较，结果显示克雷伯菌和假单胞菌败血症的发病率有所增加。相比之下，大肠杆菌感染的发病率已从56.8%显著下降至14.3%。在过去十年中，金黄色葡萄球菌一直是主要的革兰氏阳性病原体，而B族链球菌（GBS）疾病很少见。一个重要的发现是，在过去5年中出现了对庆大霉素耐药的大肠杆菌和变形杆菌菌株。新生儿败血症的总发病率为5.6/1000活产，死亡率为30.6%。
