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尼日利亚贝宁城的新生儿败血症。74例病例回顾。

Neonatal septicaemia in Benin City, Nigeria. A review of 74 cases.

作者信息

Omene J A

出版信息

Trop Geogr Med. 1979 Mar;31(1):35-9.

PMID:384626
Abstract

Seventy four cases of neonatal septicaemia seen at the University of Benin Teaching Hospital (UBTH) over a 3-year period were analysed. The incidence was 6.1 per 1,000 live births. Fifty five percent of the infants were low birth weight. The predisposing perinatal problems were asphyxia, prolonged rupture of membrane and peripartum maternal fever. E. coli and Staphylococcus aureus were the most important aetiologic pathogens; both of which were associated with a high mortality rate. The overall mortality rate was 41.5%. On the basis of the organisms isolated and their sensitivity patterns, it is suggested that the initial treatment for neonatal septicaemia should include cloxacillin and gentamycin.

摘要

对贝宁大学教学医院(UBTH)在3年期间收治的74例新生儿败血症病例进行了分析。发病率为每1000例活产6.1例。55%的婴儿为低体重儿。围产期的易感问题包括窒息、胎膜早破和产时母体发热。大肠杆菌和金黄色葡萄球菌是最重要的病原体;这两种病原体都与高死亡率相关。总体死亡率为41.5%。根据分离出的病原体及其药敏模式,建议新生儿败血症的初始治疗应包括氯唑西林和庆大霉素。

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